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2az5
From Proteopedia
(Difference between revisions)
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==Crystal Structure of TNF-alpha with a small molecule inhibitor== | ==Crystal Structure of TNF-alpha with a small molecule inhibitor== | ||
<StructureSection load='2az5' size='340' side='right' caption='[[2az5]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='2az5' size='340' side='right' caption='[[2az5]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=307:6,7-DIMETHYL-3-[(METHYL{2-[METHYL({1-[3-(TRIFLUOROMETHYL)PHENYL]-1H-INDOL-3-YL}METHYL)AMINO]ETHYL}AMINO)METHYL]-4H-CHROMEN-4-ONE'>307</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=307:6,7-DIMETHYL-3-[(METHYL{2-[METHYL({1-[3-(TRIFLUOROMETHYL)PHENYL]-1H-INDOL-3-YL}METHYL)AMINO]ETHYL}AMINO)METHYL]-4H-CHROMEN-4-ONE'>307</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TNF, TNFA, TNFSF2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TNF, TNFA, TNFSF2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2az5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2az5 OCA], [http://pdbe.org/2az5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2az5 RCSB], [http://www.ebi.ac.uk/pdbsum/2az5 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2az5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2az5 OCA], [http://pdbe.org/2az5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2az5 RCSB], [http://www.ebi.ac.uk/pdbsum/2az5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2az5 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/az/2az5_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/az/2az5_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</div> | </div> | ||
<div class="pdbe-citations 2az5" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2az5" style="background-color:#fffaf0;"></div> | ||
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| - | ==See Also== | ||
| - | *[[Tumor necrosis factor|Tumor necrosis factor]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 06:28, 7 February 2018
Crystal Structure of TNF-alpha with a small molecule inhibitor
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