This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5muc
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the FimH lectin domain in complex with 1,5-Anhydromannitol== | |
| - | + | <StructureSection load='5muc' size='340' side='right' caption='[[5muc]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5muc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MUC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MUC FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AH2:1,5-Anhydromannitol'>AH2</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5muc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5muc OCA], [http://pdbe.org/5muc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5muc RCSB], [http://www.ebi.ac.uk/pdbsum/5muc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5muc ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FIMH_ECOLI FIMH_ECOLI]] Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Ernst, B]] | ||
| + | [[Category: Jakob, R P]] | ||
| + | [[Category: Maier, T]] | ||
| + | [[Category: Rabbani, S]] | ||
| + | [[Category: Bladder infection]] | ||
| + | [[Category: Carbohydrate]] | ||
| + | [[Category: Fimh]] | ||
| + | [[Category: Lectin]] | ||
| + | [[Category: Sugar binding protein]] | ||
| + | [[Category: Upec]] | ||
| + | [[Category: Uti]] | ||
Revision as of 06:21, 15 February 2018
Crystal structure of the FimH lectin domain in complex with 1,5-Anhydromannitol
| |||||||||||
Categories: Ernst, B | Jakob, R P | Maier, T | Rabbani, S | Bladder infection | Carbohydrate | Fimh | Lectin | Sugar binding protein | Upec | Uti
