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2ewa
From Proteopedia
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|SITE= | |SITE= | ||
|LIGAND= <scene name='pdbligand=SB2:4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE'>SB2</scene> | |LIGAND= <scene name='pdbligand=SB2:4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE'>SB2</scene> | ||
| - | |ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span> |
|GENE= Mapk14, Crk1, Csbp1, Csbp2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus]) | |GENE= Mapk14, Crk1, Csbp1, Csbp2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ewa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ewa OCA], [http://www.ebi.ac.uk/pdbsum/2ewa PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ewa RCSB]</span> | ||
}} | }} | ||
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[[Category: Michot, N.]] | [[Category: Michot, N.]] | ||
[[Category: Pouzieux, S.]] | [[Category: Pouzieux, S.]] | ||
| - | [[Category: SB2]] | ||
[[Category: dfg out]] | [[Category: dfg out]] | ||
[[Category: map kinase]] | [[Category: map kinase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:54:38 2008'' |
Revision as of 23:54, 30 March 2008
| |||||||
| , resolution 2.1Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Gene: | Mapk14, Crk1, Csbp1, Csbp2 (Mus musculus) | ||||||
| Activity: | Non-specific serine/threonine protein kinase, with EC number 2.7.11.1 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Dual binding mode of pyridinylimidazole to MAP kinase p38
About this Structure
2EWA is a Single protein structure of sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
NMR characterization of kinase p38 dynamics in free and ligand-bound forms., Vogtherr M, Saxena K, Hoelder S, Grimme S, Betz M, Schieborr U, Pescatore B, Robin M, Delarbre L, Langer T, Wendt KU, Schwalbe H, Angew Chem Int Ed Engl. 2006 Jan 30;45(6):993-7. PMID:16374788
Page seeded by OCA on Mon Mar 31 02:54:38 2008
