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5oi8
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Dissociation of biochemical and antiretroviral activities of Integrase-LEDGF Allosteric Inhibitors revealed by resistance of A125 polymorphic HIV-1== | |
| - | + | <StructureSection load='5oi8' size='340' side='right' caption='[[5oi8]], [[Resolution|resolution]] 2.35Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5oi8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OI8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9VN:(2~{S})-2-[4-(4,4-dimethylcyclohexen-1-yl)-2-methyl-5-pyridin-4-yl-thiophen-3-yl]-2-[(2-methylpropan-2-yl)oxy]ethanoic+acid'>9VN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr> |
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4lh4|4lh4]]</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oi8 OCA], [http://pdbe.org/5oi8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oi8 RCSB], [http://www.ebi.ac.uk/pdbsum/5oi8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oi8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Benarous, R]] | ||
[[Category: Ruff, M]] | [[Category: Ruff, M]] | ||
| - | [[Category: | + | [[Category: Catalytic core domain]] |
| + | [[Category: Hiv-1]] | ||
| + | [[Category: Integrase]] | ||
| + | [[Category: Viral protein]] | ||
Revision as of 04:59, 8 March 2018
Dissociation of biochemical and antiretroviral activities of Integrase-LEDGF Allosteric Inhibitors revealed by resistance of A125 polymorphic HIV-1
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