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6ayv
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of fructose-1,6-bisphosphatase T84A from Mycobacterium tuberculosis== | |
| - | + | <StructureSection load='6ayv' size='340' side='right' caption='[[6ayv]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ayv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AYV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AYV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr> |
| - | [[Category: Gutka, H | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ayv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ayv OCA], [http://pdbe.org/6ayv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ayv RCSB], [http://www.ebi.ac.uk/pdbsum/6ayv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ayv ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLPX_MYCTO GLPX_MYCTO]] Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Seems to be the major FBPase of M.tuberculosis and to play a key role in gluconeogenesis for conversion of lipid carbon into cell wall glycans. Does not display activity against inositol 1-phosphate (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Fructose-bisphosphatase]] | ||
| + | [[Category: Abad-Zapatero, C]] | ||
| + | [[Category: Gutka, H J]] | ||
| + | [[Category: Movahedzadeh, F]] | ||
[[Category: Wolf, N]] | [[Category: Wolf, N]] | ||
| - | [[Category: | + | [[Category: 6-bisphosphatase]] |
| - | [[Category: | + | [[Category: Class ii phosphatase]] |
| + | [[Category: Fructose-1]] | ||
| + | [[Category: Gluconeogenesis]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Mycobacterium tuberculosis]] | ||
Revision as of 06:29, 14 March 2018
Crystal structure of fructose-1,6-bisphosphatase T84A from Mycobacterium tuberculosis
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