This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6ffn
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='6ffn' size='340' side='right' caption='[[6ffn]], [[Resolution|resolution]] 1.75Å' scene=''> | <StructureSection load='6ffn' size='340' side='right' caption='[[6ffn]], [[Resolution|resolution]] 1.75Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6ffn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FFN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FFN FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6ffn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hrv-2 Hrv-2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FFN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FFN FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D8K:~{N}-[(5~{S},8~{S},11~{S},15~{R})-8-[(4-fluorophenyl)methyl]-5-(hydroxymethyl)-2,7,10,14-tetrakis(oxidanylidene)-1,6,9,13-tetrazabicyclo[13.3.0]octadecan-11-yl]-5-methyl-1,2-oxazole-3-carboxamide'>D8K</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D8K:~{N}-[(5~{S},8~{S},11~{S},15~{R})-8-[(4-fluorophenyl)methyl]-5-(hydroxymethyl)-2,7,10,14-tetrakis(oxidanylidene)-1,6,9,13-tetrazabicyclo[13.3.0]octadecan-11-yl]-5-methyl-1,2-oxazole-3-carboxamide'>D8K</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ffn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ffn OCA], [http://pdbe.org/6ffn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ffn RCSB], [http://www.ebi.ac.uk/pdbsum/6ffn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ffn ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ffn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ffn OCA], [http://pdbe.org/6ffn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ffn RCSB], [http://www.ebi.ac.uk/pdbsum/6ffn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ffn ProSAT]</span></td></tr> | ||
| Line 18: | Line 18: | ||
</div> | </div> | ||
<div class="pdbe-citations 6ffn" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 6ffn" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[3C protease|3C protease]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Hrv-2]] | ||
[[Category: Farady, C]] | [[Category: Farady, C]] | ||
[[Category: Wiesmann, C]] | [[Category: Wiesmann, C]] | ||
Current revision
Structure-based design and synthesis of macrocyclic human rhinovirus 3C protease inhibitors
| |||||||||||
Categories: Hrv-2 | Farady, C | Wiesmann, C | 3c protease | Hydrolase | Inhibitor | Rhinovirus
