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1up5

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==CHICKEN CALMODULIN==
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==Chicken Calmodulin==
<StructureSection load='1up5' size='340' side='right' caption='[[1up5]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='1up5' size='340' side='right' caption='[[1up5]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1up5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UP5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UP5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1up5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UP5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UP5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a29|1a29]], [[1ahr|1ahr]], [[1aji|1aji]], [[1ak8|1ak8]], [[1cdl|1cdl]], [[1cdm|1cdm]], [[1cfc|1cfc]], [[1cfd|1cfd]], [[1cff|1cff]], [[1ckk|1ckk]], [[1cll|1cll]], [[1cm1|1cm1]], [[1cm4|1cm4]], [[1cmf|1cmf]], [[1cmg|1cmg]], [[1ctr|1ctr]], [[1deg|1deg]], [[1dmo|1dmo]], [[1f70|1f70]], [[1f71|1f71]], [[1fw4|1fw4]], [[1iq5|1iq5]], [[1iwq|1iwq]], [[1j7o|1j7o]], [[1j7p|1j7p]], [[1k90|1k90]], [[1k93|1k93]], [[1l7z|1l7z]], [[1lin|1lin]], [[1lvc|1lvc]], [[1mux|1mux]], [[1nkf|1nkf]], [[1nwd|1nwd]], [[1qiv|1qiv]], [[1qiw|1qiw]], [[2cln|2cln]], [[3cln|3cln]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a29|1a29]], [[1ahr|1ahr]], [[1aji|1aji]], [[1ak8|1ak8]], [[1cdl|1cdl]], [[1cdm|1cdm]], [[1cfc|1cfc]], [[1cfd|1cfd]], [[1cff|1cff]], [[1ckk|1ckk]], [[1cll|1cll]], [[1cm1|1cm1]], [[1cm4|1cm4]], [[1cmf|1cmf]], [[1cmg|1cmg]], [[1ctr|1ctr]], [[1deg|1deg]], [[1dmo|1dmo]], [[1f70|1f70]], [[1f71|1f71]], [[1fw4|1fw4]], [[1iq5|1iq5]], [[1iwq|1iwq]], [[1j7o|1j7o]], [[1j7p|1j7p]], [[1k90|1k90]], [[1k93|1k93]], [[1l7z|1l7z]], [[1lin|1lin]], [[1lvc|1lvc]], [[1mux|1mux]], [[1nkf|1nkf]], [[1nwd|1nwd]], [[1qiv|1qiv]], [[1qiw|1qiw]], [[2cln|2cln]], [[3cln|3cln]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1up5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1up5 OCA], [http://pdbe.org/1up5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1up5 RCSB], [http://www.ebi.ac.uk/pdbsum/1up5 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1up5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1up5 OCA], [http://pdbe.org/1up5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1up5 RCSB], [http://www.ebi.ac.uk/pdbsum/1up5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1up5 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/CALM_CHICK CALM_CHICK]] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/up/1up5_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/up/1up5_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1up5 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chick]]
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[[Category: Gallus gallus]]
[[Category: Rupp, B]]
[[Category: Rupp, B]]
[[Category: Wilson, M A]]
[[Category: Wilson, M A]]

Revision as of 06:50, 28 March 2018

Chicken Calmodulin

1up5, resolution 1.90Å

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