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2uwj
From Proteopedia
(Difference between revisions)
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| - | == | + | |
| + | ==Structure of the heterotrimeric complex which regulates type III secretion needle formation== | ||
<StructureSection load='2uwj' size='340' side='right' caption='[[2uwj]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='2uwj' size='340' side='right' caption='[[2uwj]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2uwj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UWJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UWJ FirstGlance]. <br> | <table><tr><td colspan='2'>[[2uwj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UWJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UWJ FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uwj OCA], [http://pdbe.org/2uwj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2uwj RCSB], [http://www.ebi.ac.uk/pdbsum/2uwj PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uwj OCA], [http://pdbe.org/2uwj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2uwj RCSB], [http://www.ebi.ac.uk/pdbsum/2uwj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2uwj ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/PSCG_PSEAE PSCG_PSEAE]] Prevents premature polymerization of PscF, along with PscE, within the cytoplasm. Required for type III secretion needle assembly. Also required for cytotoxicity by influencing PscF levels. | + | [[http://www.uniprot.org/uniprot/PSCG_PSEAE PSCG_PSEAE]] Prevents premature polymerization of PscF, along with PscE, within the cytoplasm. Required for type III secretion needle assembly. Also required for cytotoxicity by influencing PscF levels. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uw/2uwj_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uw/2uwj_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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[[Category: Bacterial pathogenicity]] | [[Category: Bacterial pathogenicity]] | ||
[[Category: Chaperone]] | [[Category: Chaperone]] | ||
| + | [[Category: Coiled coil]] | ||
[[Category: Needle formation]] | [[Category: Needle formation]] | ||
[[Category: Type iii secretion]] | [[Category: Type iii secretion]] | ||
[[Category: Virulence]] | [[Category: Virulence]] | ||
Revision as of 06:53, 28 March 2018
Structure of the heterotrimeric complex which regulates type III secretion needle formation
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