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Vpr protein
From Proteopedia
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== Function == | == Function == | ||
| - | '''Vpr protein''' (Vpr) or '''viral protein R''' is | + | '''Vpr protein''' (Vpr) or '''viral protein R''' is a 96 amino acid protein which encoded by the human Immunodeficiency virus type 1 ([[HIV-1]]). Vpr has several roles in the progression of HIV-1 disease, including regulation the HIV-1 pre-integration complex nuclear import and virus replication in non-dividing macrophages<ref>PMID:10371671</ref>. |
For details see [[HIV and accessory proteins]]. | For details see [[HIV and accessory proteins]]. | ||
Revision as of 19:02, 2 April 2018
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3D Structures of Vpr protein
Updated on 02-April-2018
1m8l – Vpr - NMR - HIV-1
1esx - synthetic Vpr - NMR - HIV-1
5jk7 – Vpr + DDB1 + DCAF-1 + UNG2 – X-ray solution - HIV-1
1x9v – Dimeric structure of the Vpr C-terminal domain - NMR
1vpc - C-terminal domain of Vpr - NMR - HIV-1
1fi0 - Vpr residues 13-33 in micelles - NMR - HIV-1
1bde - NMR solution of Vpr peptides connected to cell cycle arrest and nuclear provirus transfer
5b56 - Importin subunit alpha-1 + Vpr C-terminal domain - crystallographic analysis
1kzs, 1kzt, 1kzv - Vpr residues 34-51 - NMR - HIV-1
1dsj - Vpr residues 50-75 - NMR - HIV-1
1ceu - Vpr N-terminal domain - NMR - HIV-1
1dsk - Vpr residues 59-86 - NMR - HIV-1
4u1s - HLA-I + Beta-2-microglobulin + Vpr protein - X-ray diffraction
