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Complement factor

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</StructureSection>
</StructureSection>
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==3D structures of complement factor H==
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==3D structures of complement factor==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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**[[4j38]] – hCFH 19-20 sushi domains (mutant) + outer surface protein E <br />
**[[4j38]] – hCFH 19-20 sushi domains (mutant) + outer surface protein E <br />
**[[4k12]] – hCFH 9 sushi domain + choline binding protein A <br />
**[[4k12]] – hCFH 9 sushi domain + choline binding protein A <br />
 +
**[[5nbq]] – hCFH + complement C3 a chain + outer surface protein<br />
 +
**[[5o32]] – hCFH + hCFI + complement C3 a+b chains <br />
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**[[5o35]] – hCFH + complement C3 a chain <br />
 +
 +
*Complement factor B
 +
 +
**[[2ok5]] – hCFB residues 26-764<br />
 +
**[[1dle]] – hCFB serine protease domain residues 470-764<br />
 +
**[[1q0p]] – hCFB residues 254-476 (mutant) <br />
 +
**[[1rrk]] – hCFB BB fragment residues 243-764 (mutant) <br />
 +
 +
*Complement factor B complexes
 +
 +
**[[1rs0]] – hCFB BB fragment (mutant) + DIP<br />
 +
**[[1rtk]] – hCFB BB fragment (mutant) + guanidinobenzoate<br />
 +
**[[2xwb]] – hCFB (mutant) + hCFD (mutant) + complement C3B a’+b chains<br />
 +
**[[2xwj]] – hCFB (mutant) + complement C3 a+b chains<br />
 +
**[[3hrz]], [[3hs0]] – hCFB (mutant) + cobra venom factor<br />
 +
 +
*Complement factor D
 +
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**[[1dsu]], [[1hfd]] – hCFD <br />
 +
**[[1dst]], [[2xw9]], [[2xwa]], [[4cbn]], [[4cbo]] – hCFD (mutant) <br />
 +
**[[1fdp]] – hCFD proenzyme <br />
 +
 +
*Complement factor D complexes
 +
 +
**[[1bio]], [[1dfp]], [[1dic]], [[5fbe]], [[5fbi]], [[5fck]], [[5fcr]], [[5mt0]], [[5mt4]], [[5nar]], [[5nat]], [[5naw]], [[5nb6]], [[5nb7]], [[5nba]], [[5tca]], [[5tcc]] – hCFD + inhibitor <br />
 +
**[[4d9r]] – hCFD + antibody<br />
 +
 +
*Complement factor I
 +
 +
**[[2xrc]] – hCFI <br />
 +
}}
}}

Revision as of 08:01, 15 April 2018

Structure of human complement factor H 19-20 sushi domains (magenta) complex with complement C3 (green) and glycerol (PDB code 3oxu).

Drag the structure with the mouse to rotate

3D structures of complement factor

Updated on 15-April-2018



References

  1. ↑ Rodriguez de Cordoba S, Esparza-Gordillo J, Goicoechea de Jorge E, Lopez-Trascasa M, Sanchez-Corral P. The human complement factor H: functional roles, genetic variations and disease associations. Mol Immunol. 2004 Jun;41(4):355-67. PMID:15163532 doi:10.1016/j.molimm.2004.02.005

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Jaime Prilusky

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