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2h11

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|PDB= 2h11 |SIZE=350|CAPTION= <scene name='initialview01'>2h11</scene>, resolution 1.89&Aring;
|PDB= 2h11 |SIZE=350|CAPTION= <scene name='initialview01'>2h11</scene>, resolution 1.89&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene> and <scene name='pdbligand=B3P:2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>B3P</scene>
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|LIGAND= <scene name='pdbligand=B3P:2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>B3P</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Thiopurine_S-methyltransferase Thiopurine S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.67 2.1.1.67]
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thiopurine_S-methyltransferase Thiopurine S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.67 2.1.1.67] </span>
|GENE= TPMT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= TPMT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h11 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h11 OCA], [http://www.ebi.ac.uk/pdbsum/2h11 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2h11 RCSB]</span>
}}
}}
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[[Category: Cheng, X.]]
[[Category: Cheng, X.]]
[[Category: Horton, J R.]]
[[Category: Horton, J R.]]
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[[Category: B3P]]
 
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[[Category: SAH]]
 
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[[Category: SCN]]
 
[[Category: binary protein-cofactor complex]]
[[Category: binary protein-cofactor complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:11:18 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:23:59 2008''

Revision as of 00:24, 31 March 2008


PDB ID 2h11

Drag the structure with the mouse to rotate
, resolution 1.89Å
Ligands: , ,
Gene: TPMT (Homo sapiens)
Activity: Thiopurine S-methyltransferase, with EC number 2.1.1.67
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Amino-terminal Truncated Thiopurine S-Methyltransferase Complexed with S-Adenosyl-L-Homocysteine


Disease

Known disease associated with this structure: 6-mercaptopurine sensitivity OMIM:[187680]

About this Structure

2H11 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Mon Mar 31 03:23:59 2008

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