Deoxyuridine 5'-triphosphate nucleotidohydrolase
From Proteopedia
(Difference between revisions)
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**[[1q5u]] - hDUTP – human<br /> | **[[1q5u]] - hDUTP – human<br /> | ||
**[[4lhr]] - DUTP – ''Burkholderia thailandensis''<br /> | **[[4lhr]] - DUTP – ''Burkholderia thailandensis''<br /> | ||
| + | **[[3h6x]] - DUTP – ''Streptococcus mutans''<br /> | ||
| + | **[[5myf]] - SaDUTP – ''Staphylococcus aureus''<br /> | ||
| + | **[[5myi]] - SaDUTP (mutant)<br /> | ||
*DUTP binary complexes | *DUTP binary complexes | ||
| Line 47: | Line 50: | ||
**[[1smc]] - MtDUTP + dUTP<br /> | **[[1smc]] - MtDUTP + dUTP<br /> | ||
**[[4gcy]] - MtDUTP (mutant) + dUTP<br /> | **[[4gcy]] - MtDUTP (mutant) + dUTP<br /> | ||
| + | **[[4a6a]] - MtDUTP (mutant) + dTTP<br /> | ||
**[[1vyq]], [[3t60]], [[3t64]], [[3t6y]], [[3t70]] - PfDUTP + uridine derivative inhibitor – ''Plasmodium falciparum''<br /> | **[[1vyq]], [[3t60]], [[3t64]], [[3t6y]], [[3t70]] - PfDUTP + uridine derivative inhibitor – ''Plasmodium falciparum''<br /> | ||
**[[2y8c]] - PfDUTP + trityl ligand<br /> | **[[2y8c]] - PfDUTP + trityl ligand<br /> | ||
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**[[4ooq]], [[2pc5]] – AtDUTP + Mg – ''Arabidopsis thaliana''<br /> | **[[4ooq]], [[2pc5]] – AtDUTP + Mg – ''Arabidopsis thaliana''<br /> | ||
**[[4mz5]], [[4mz6]] – hDUTP + importin subunit α-1<br /> | **[[4mz5]], [[4mz6]] – hDUTP + importin subunit α-1<br /> | ||
| + | **[[5h4j]] - hDUTP + inhibitor<br /> | ||
| + | **[[3zf0]], [[3zf1]], [[3zf2]], [[3zf3]], [[3zf4]], [[3zf5]], [[3zf6]], [[5cct]], [[5nyz]], [[5nz2]] - SpDUTP (mutant) + dUTP derivative – ''Staphylococcus'' phage 80α<br /> | ||
| + | **[[5cco]] - SpDUTP + dUMP <br /> | ||
| + | **[[4gv8]] - DUTP + dUTP derivative – ''Staphylococcus'' phage 11<br /> | ||
| + | **[[4wrk]] - DUTP (mutant) + dUTP derivative – ''Staphylococcus'' phage φ11<br /> | ||
| + | **[[5myd]] - DUTP + dUTP derivative – ''Staphylococcus'' <br /> | ||
*DUTP ternary complexes | *DUTP ternary complexes | ||
Revision as of 06:40, 24 April 2018
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3D structures of dUTPase
Updated on 24-April-2018
References
- ↑ Vertessy BG, Toth J. Keeping uracil out of DNA: physiological role, structure and catalytic mechanism of dUTPases. Acc Chem Res. 2009 Jan 20;42(1):97-106. PMID:18837522 doi:10.1021/ar800114w
- ↑ Moroz OV, Harkiolaki M, Galperin MY, Vagin AA, Gonzalez-Pacanowska D, Wilson KS. The crystal structure of a complex of Campylobacter jejuni dUTPase with substrate analogue sheds light on the mechanism and suggests the "basic module" for dimeric d(C/U)TPases. J Mol Biol. 2004 Oct 1;342(5):1583-97. PMID:15364583 doi:10.1016/j.jmb.2004.07.050
