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6d9j

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m (Protected "6d9j" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{Large structure}}
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==Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1.==
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The entry 6d9j is ON HOLD
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<StructureSection load='6d9j' size='340' side='right' caption='[[6d9j]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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== Structural highlights ==
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Authors: Pisareva, V.P., Pisarev, A.V., Fernandez, I.S.
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<table><tr><td colspan='2'>[[6d9j]] is a 85 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D9J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D9J FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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Description: Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1.
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d9j OCA], [http://pdbe.org/6d9j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d9j RCSB], [http://www.ebi.ac.uk/pdbsum/6d9j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d9j ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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[[Category: Pisareva, V.P]]
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{{Large structure}}
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[[Category: Pisarev, A.V]]
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== Function ==
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[[Category: Fernandez, I.S]]
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[[http://www.uniprot.org/uniprot/EF2_HUMAN EF2_HUMAN]] Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. [[http://www.uniprot.org/uniprot/U3KPD5_RABIT U3KPD5_RABIT]] Binds to the 23S rRNA.[RuleBase:RU000576] [[http://www.uniprot.org/uniprot/G1SS70_RABIT G1SS70_RABIT]] May play a role during erythropoiesis through regulation of transcription factor DDIT3.[HAMAP-Rule:MF_03122]
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__TOC__
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</StructureSection>
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[[Category: Oryctolagus cuniculus]]
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[[Category: Fernandez, I S]]
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[[Category: Pisarev, A V]]
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[[Category: Pisareva, V P]]
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[[Category: Crpv ire]]
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[[Category: Mammalian]]
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[[Category: Ribosome]]

Revision as of 05:59, 6 June 2018

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Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1.

6d9j, resolution 3.20Å

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