This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2k6o
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | |||
==Human LL-37 Structure== | ==Human LL-37 Structure== | ||
<StructureSection load='2k6o' size='340' side='right' caption='[[2k6o]], [[NMR_Ensembles_of_Models | 4 NMR models]]' scene=''> | <StructureSection load='2k6o' size='340' side='right' caption='[[2k6o]], [[NMR_Ensembles_of_Models | 4 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2k6o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K6O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K6O FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[2k6o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. The June 2013 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Dermcidin'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2013_6 10.2210/rcsb_pdb/mom_2013_6]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K6O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K6O FirstGlance]. <br> |
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fbu|2fbu]], [[2fbs|2fbs]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fbu|2fbu]], [[2fbs|2fbs]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CAMP, CAP18, FALL39, HSD26 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CAMP, CAP18, FALL39, HSD26 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k6o OCA], [http://pdbe.org/2k6o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k6o RCSB], [http://www.ebi.ac.uk/pdbsum/2k6o PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k6o OCA], [http://pdbe.org/2k6o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k6o RCSB], [http://www.ebi.ac.uk/pdbsum/2k6o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2k6o ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| Line 13: | Line 14: | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k6/2k6o_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k6/2k6o_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k6o ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
| Line 32: | Line 33: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Dermcidin]] | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: Wang, G]] | [[Category: Wang, G]] | ||
[[Category: Antibiotic]] | [[Category: Antibiotic]] | ||
Revision as of 10:26, 18 July 2018
Human LL-37 Structure
| |||||||||||
Categories: Dermcidin | Human | RCSB PDB Molecule of the Month | Wang, G | Antibiotic | Antimicrobial | Antimicrobial peptide | Antimicrobial protein | Bacterial membrane targeting | Cleavage on pair of basic residue | Human cathelicidin | Human host defense peptide | Ll-37 | Pyrrolidone carboxylic acid | Secreted
