This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5oc9
From Proteopedia
(Difference between revisions)
m (Protected "5oc9" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of human TMEM16K / Anoctamin 10== | |
| - | + | <StructureSection load='5oc9' size='340' side='right' caption='[[5oc9]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5oc9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OC9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OC9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=79M:(2R)-2,3-DIHYDROXYPROPYL+(7Z)-HEXADEC-7-ENOATE'>79M</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5oc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5oc9 OCA], [http://pdbe.org/5oc9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5oc9 RCSB], [http://www.ebi.ac.uk/pdbsum/5oc9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5oc9 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/ANO10_HUMAN ANO10_HUMAN]] Adult-onset autosomal recessive cerebellar ataxia. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ANO10_HUMAN ANO10_HUMAN]] Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1.<ref>PMID:20056604</ref> <ref>PMID:22946059</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: BORKOWSKA, O]] | ||
| + | [[Category: Bountra, C]] | ||
| + | [[Category: Burgess-Brown, N A]] | ||
| + | [[Category: Bushell, S R]] | ||
| + | [[Category: CHALK, R]] | ||
| + | [[Category: Carpenter, E P]] | ||
| + | [[Category: Chu, A]] | ||
| + | [[Category: Edwards, A M]] | ||
| + | [[Category: Kupinska, K]] | ||
| + | [[Category: Love, J]] | ||
| + | [[Category: Mukhopadhyay, S]] | ||
| + | [[Category: Pike, A C.W]] | ||
| + | [[Category: Rotty, B]] | ||
| + | [[Category: Structural genomic]] | ||
| + | [[Category: Shrestha, L]] | ||
| + | [[Category: Tessitore, A]] | ||
| + | [[Category: Calcium activation]] | ||
| + | [[Category: Lipid transport]] | ||
| + | [[Category: Membrane protein]] | ||
| + | [[Category: Sgc]] | ||
| + | [[Category: Transport protein]] | ||
Revision as of 07:07, 25 July 2018
Crystal Structure of human TMEM16K / Anoctamin 10
| |||||||||||
Categories: Arrowsmith, C H | BORKOWSKA, O | Bountra, C | Burgess-Brown, N A | Bushell, S R | CHALK, R | Carpenter, E P | Chu, A | Edwards, A M | Kupinska, K | Love, J | Mukhopadhyay, S | Pike, A C.W | Rotty, B | Structural genomic | Shrestha, L | Tessitore, A | Calcium activation | Lipid transport | Membrane protein | Sgc | Transport protein
