Sandbox bcce77
From Proteopedia
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==Your Heading Here (maybe something like 'Structure')== | ==Your Heading Here (maybe something like 'Structure')== | ||
<StructureSection load='3bdp' size='420' side='right' caption='DNA Pol I with DNA' scene=''> | <StructureSection load='3bdp' size='420' side='right' caption='DNA Pol I with DNA' scene=''> | ||
- | Structure of DNA Pol I <ref> pmid: | + | Structure of DNA Pol I <ref> pmid:9440698 </ref> |
This is a default text for your page '''Sandbox bcce77'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is a default text for your page '''Sandbox bcce77'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
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== Function == | == Function == | ||
Copies dsDNA to two new daughter strands. | Copies dsDNA to two new daughter strands. | ||
+ | You can see <scene name='79/793372/Pol_dna_cart/1'>polymerase with DNA</scene> highlighted in red. | ||
+ | Much of the sequence is <scene name='79/793372/Pol_backbone_cons/2'>highly conserved</scene>. You can see the <scene name='79/793372/Pol_backbone_highlight/4'>phosphate background</scene> of the DNA strands. | ||
+ | |||
== Disease == | == Disease == | ||
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== Structural highlights == | == Structural highlights == | ||
- | + | Metal ions like Zn are important in the active site of DNA Polymerase | |
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
Current revision
Your Heading Here (maybe something like 'Structure')
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References
- ↑ Kiefer JR, Mao C, Braman JC, Beese LS. Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. Nature. 1998 Jan 15;391(6664):304-7. PMID:9440698 doi:10.1038/34693
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644