Pantothenate kinase
From Proteopedia
(Difference between revisions)
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| - | <StructureSection load='2f9w' size=' | + | <StructureSection load='2f9w' size='350' side='right' caption='Pantothenate kinase III dimer complex with pantothenate, glycerol and ethane diol, [[2f9w]]' scene='52/525168/Cv/1' pspeed='8'> |
== Function == | == Function == | ||
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**[[1esn]] - EcPanK + ANP<br /> | **[[1esn]] - EcPanK + ANP<br /> | ||
**[[1sq5]] - EcPanK + ADP + PAU<br /> | **[[1sq5]] - EcPanK + ADP + PAU<br /> | ||
| - | **[[3tqc]] - PanK – ''Coxiella burnetii'' | + | **[[3tqc]] - PanK – ''Coxiella burnetii''<br /> |
| + | **[[5xlv]] - MtPanK – ''Mycobacterium tuberculosis''<br /> | ||
| + | **[[5xlw]], [[5xmb]] - MtPanK (mutant)<br /> | ||
*PanK I binary complex | *PanK I binary complex | ||
| - | **[[2ges]], [[2get]], [[2zs7]], [[2geu]], [[2gev]] - MtPanK + CoA derivative | + | **[[2ges]], [[2get]], [[2zs7]], [[2geu]], [[2gev]] - MtPanK + CoA derivative <br /> |
**[[2zs8]], [[2zsb]] - MtPanK + ADP<br /> | **[[2zs8]], [[2zsb]] - MtPanK + ADP<br /> | ||
**[[3af1]] - MtPanK + GDP <br /> | **[[3af1]] - MtPanK + GDP <br /> | ||
Revision as of 11:08, 15 August 2018
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3D structures of pantothenate kinase
Updated on 15-August-2018
References
- ↑ . PanK is regulated by feedback inhibition by CoA and its thioesters.PMID:9890959
- ↑ Pellecchia MT, Valente EM, Cif L, Salvi S, Albanese A, Scarano V, Bonuccelli U, Bentivoglio AR, D'Amico A, Marelli C, Di Giorgio A, Coubes P, Barone P, Dallapiccola B. The diverse phenotype and genotype of pantothenate kinase-associated neurodegeneration. Neurology. 2005 May 24;64(10):1810-2. PMID:15911822 doi:http://dx.doi.org/10.1212/01.WNL.0000161843.52641.EC
- ↑ Hong BS, Yun MK, Zhang YM, Chohnan S, Rock CO, White SW, Jackowski S, Park HW, Leonardi R. Prokaryotic type II and type III pantothenate kinases: The same monomer fold creates dimers with distinct catalytic properties. Structure. 2006 Aug;14(8):1251-61. PMID:16905099 doi:10.1016/j.str.2006.06.008
