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2pmx

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|PDB= 2pmx |SIZE=350|CAPTION= <scene name='initialview01'>2pmx</scene>, resolution 2.270&Aring;
|PDB= 2pmx |SIZE=350|CAPTION= <scene name='initialview01'>2pmx</scene>, resolution 2.270&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene> and <scene name='pdbligand=CIT:CITRIC ACID'>CIT</scene>
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|LIGAND= <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>
|ACTIVITY=
|ACTIVITY=
|GENE= KRAS, KRAS2, RASK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= KRAS, KRAS2, RASK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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|DOMAIN=
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pmx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pmx OCA], [http://www.ebi.ac.uk/pdbsum/2pmx PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pmx RCSB]</span>
}}
}}
'''Human K-Ras in complex with a GTP analogue'''
'''Human K-Ras in complex with a GTP analogue'''
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==Disease==
 
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Known diseases associated with this structure: Bladder cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190070 190070]], Breast cancer, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190070 190070]], Costello syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190070 190070]], Leukemia, acute myelogenous OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190070 190070]], Lung cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190070 190070]], Noonan syndrome 3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190070 190070]], Pancreatic carcinoma, somatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190070 190070]], Stomach cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190070 190070]]
 
==About this Structure==
==About this Structure==
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[[Category: Tong, Y.]]
[[Category: Tong, Y.]]
[[Category: Weigelt, J.]]
[[Category: Weigelt, J.]]
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[[Category: CIT]]
 
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[[Category: GNP]]
 
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[[Category: MG]]
 
[[Category: cancer]]
[[Category: cancer]]
[[Category: gtp analogue]]
[[Category: gtp analogue]]
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[[Category: structural genomics consortium]]
[[Category: structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:15:01 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:38:09 2008''

Revision as of 01:38, 31 March 2008


PDB ID 2pmx

Drag the structure with the mouse to rotate
, resolution 2.270Å
Ligands: , ,
Gene: KRAS, KRAS2, RASK2 (Homo sapiens)
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Human K-Ras in complex with a GTP analogue


About this Structure

2PMX is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Mon Mar 31 04:38:09 2008

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