This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2pzg
From Proteopedia
| Line 4: | Line 4: | ||
|PDB= 2pzg |SIZE=350|CAPTION= <scene name='initialview01'>2pzg</scene>, resolution 1.800Å | |PDB= 2pzg |SIZE=350|CAPTION= <scene name='initialview01'>2pzg</scene>, resolution 1.800Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand= | + | |LIGAND= <scene name='pdbligand=ATP:ADENOSINE-5'-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> |
|ACTIVITY= | |ACTIVITY= | ||
|GENE= CFTR, ABCC7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= CFTR, ABCC7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY=[[1xmi|1XMI]], [[1xmj|1XMJ]], [[2bb0|2BB0]], [[2bbs|2BBS]], [[2bbt|2BBT]], [[1r0z|1R0Z]], [[1r10|1R10]], [[2ixe|2IXE]], [[1l2t|1L2T]], [[1q12|1Q12]], [[1xef|1XEF]], [[2hyd|2HYD]], [[2pzf|2PZF]], [[2pze|2PZE]] | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pzg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pzg OCA], [http://www.ebi.ac.uk/pdbsum/2pzg PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pzg RCSB]</span> | ||
}} | }} | ||
'''Minimal human CFTR first nucleotide binding domain as a monomer''' | '''Minimal human CFTR first nucleotide binding domain as a monomer''' | ||
| - | |||
| - | ==Disease== | ||
| - | Known diseases associated with this structure: Congenital bilateral absence of vas deferens OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]], Cystic fibrosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]], Hypertrypsinemia, neonatal OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]], Pancreatitis, idiopathic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]], Sweat chloride elevation without CF OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602421 602421]] | ||
==About this Structure== | ==About this Structure== | ||
| Line 34: | Line 34: | ||
[[Category: Wasserman, S R.]] | [[Category: Wasserman, S R.]] | ||
[[Category: Zhao, X.]] | [[Category: Zhao, X.]] | ||
| - | [[Category: ATP]] | ||
| - | [[Category: GOL]] | ||
| - | [[Category: MG]] | ||
[[Category: abc transporter]] | [[Category: abc transporter]] | ||
[[Category: cftr]] | [[Category: cftr]] | ||
| Line 42: | Line 39: | ||
[[Category: nbd]] | [[Category: nbd]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:42:46 2008'' |
Revision as of 01:42, 31 March 2008
| |||||||
| , resolution 1.800Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , | ||||||
| Gene: | CFTR, ABCC7 (Homo sapiens) | ||||||
| Related: | 1XMI, 1XMJ, 2BB0, 2BBS, 2BBT, 1R0Z, 1R10, 2IXE, 1L2T, 1Q12, 1XEF, 2HYD, 2PZF, 2PZE
| ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Minimal human CFTR first nucleotide binding domain as a monomer
About this Structure
2PZG is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 04:42:46 2008
Categories: Homo sapiens | Single protein | Atwell, S. | Conners, K. | Emtage, S. | Gheyi, T. | Glenn, N R. | Hendle, J. | Lewis, H A. | Lu, F. | Rodgers, L A. | Romero, R. | Sauder, J M. | Smith, D. | Tien, H. | Wasserman, S R. | Zhao, X. | Abc transporter | Cftr | Hydrolase | Nbd
