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Thioredoxin
From Proteopedia
(Difference between revisions)
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| - | <StructureSection load='' size=' | + | <StructureSection load='' size='350' side='right' caption='Human thioredoxin (PDB entry [[1ert]])' scene='43/430885/Cv/2'> |
== Function == | == Function == | ||
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**[[4wxt]] - Trx – ''Mycobacterium avium''<br /> | **[[4wxt]] - Trx – ''Mycobacterium avium''<br /> | ||
**[[5jy5]] - Trx – ''Cryptococcus neoformans''<br /> | **[[5jy5]] - Trx – ''Cryptococcus neoformans''<br /> | ||
| - | **[[ | + | **[[6ap5]] - Trx – ''Mycobacterium thermoresistibile'' - NMR<br /> |
**[[5vo7]] - Trx – ''Mycobacterium smegmatis'' - NMR<br /> | **[[5vo7]] - Trx – ''Mycobacterium smegmatis'' - NMR<br /> | ||
**[[5dbq]] - Trx – velvetbean caterpillar<br /> | **[[5dbq]] - Trx – velvetbean caterpillar<br /> | ||
| + | **[[6bkv]] - Trx – ''Helicobacter pylori''<br /> | ||
| + | **[[6ckp]] - Trx – ''Brucella melitensis''<br /> | ||
*Thioredoxin complexes | *Thioredoxin complexes | ||
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**[[2n5a]] – yTrx-1 (mutant) reduced<br /> | **[[2n5a]] – yTrx-1 (mutant) reduced<br /> | ||
**[[2n5b]] – yTrx-1 (mutant) oxidized<br /> | **[[2n5b]] – yTrx-1 (mutant) oxidized<br /> | ||
| + | **[[6esx]] - Trx-1 – ''Caulobacter crescentus''<br /> | ||
**[[3dyr]], [[2h6y]], [[2h6z]], [[2h70]], [[2h71]], [[2h72]], [[2h73]], [[2h74]], [[2h75]], [[2h76]], [[2fch]], [[2fd3]], [[1keb]], [[2eio]], [[2eiq]], [[2eir]], [[1zcp]], [[1zzy]], [[1txx]], [[1tho]], [[4x43]], [[5hr1]] – EcTrx-1 (mutant) <br /> | **[[3dyr]], [[2h6y]], [[2h6z]], [[2h70]], [[2h71]], [[2h72]], [[2h73]], [[2h74]], [[2h75]], [[2h76]], [[2fch]], [[2fd3]], [[1keb]], [[2eio]], [[2eiq]], [[2eir]], [[1zcp]], [[1zzy]], [[1txx]], [[1tho]], [[4x43]], [[5hr1]] – EcTrx-1 (mutant) <br /> | ||
**[[1f6m]] – EcTrx-1+Trx reductase+AADP+<br /> | **[[1f6m]] – EcTrx-1+Trx reductase+AADP+<br /> | ||
Revision as of 20:32, 25 September 2018
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3D Structures of Thioredoxin
Updated on 25-September-2018
References
- ↑ Gleason FK, Holmgren A. Thioredoxin and related proteins in procaryotes. FEMS Microbiol Rev. 1988 Dec;4(4):271-97. PMID:3152490
- ↑ Sumida Y, Nakashima T, Yoh T, Furutani M, Hirohama A, Kakisaka Y, Nakajima Y, Ishikawa H, Mitsuyoshi H, Okanoue T, Kashima K, Nakamura H, Yodoi J. Serum thioredoxin levels as a predictor of steatohepatitis in patients with nonalcoholic fatty liver disease. J Hepatol. 2003 Jan;38(1):32-8. PMID:12480557
- ↑ Burke-Gaffney A, Callister ME, Nakamura H. Thioredoxin: friend or foe in human disease? Trends Pharmacol Sci. 2005 Aug;26(8):398-404. PMID:15990177 doi:http://dx.doi.org/10.1016/j.tips.2005.06.005
- ↑ Weichsel A, Gasdaska JR, Powis G, Montfort WR. Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer. Structure. 1996 Jun 15;4(6):735-51. PMID:8805557
