6dxw
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Human N-acylethanolamine-hydrolyzing acid amidase (NAAA) precursor (C126A)== | |
| - | + | <StructureSection load='6dxw' size='340' side='right' caption='[[6dxw]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6dxw]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DXW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dxw OCA], [http://pdbe.org/6dxw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dxw RCSB], [http://www.ebi.ac.uk/pdbsum/6dxw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dxw ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/NAAA_HUMAN NAAA_HUMAN]] Degrades bioactive fatty acid amides to their corresponding acids, with the following preference: N-palmitoylethanolamine > N-myristoylethanolamine > N-lauroylethanolamine = N-stearoylethanolamine > N-arachidonoylethanolamine > N-oleoylethanolamine. Also exhibits weak hydrolytic activity against the ceramides N-lauroylsphingosine and N-palmitoylsphingosine.<ref>PMID:15655246</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Gebai, A]] | ||
| + | [[Category: Gorelik, A]] | ||
| + | [[Category: Illes, K]] | ||
| + | [[Category: Nagar, B]] | ||
| + | [[Category: Piomelli, D]] | ||
| + | [[Category: Endocannabinoid]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Lipase]] | ||
Revision as of 08:05, 26 September 2018
Human N-acylethanolamine-hydrolyzing acid amidase (NAAA) precursor (C126A)
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Categories: Gebai, A | Gorelik, A | Illes, K | Nagar, B | Piomelli, D | Endocannabinoid | Hydrolase | Lipase
