6hj5
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Whitewater Arroyo virus GP1 glycoprotein at pH 5.6== | |
| - | + | <StructureSection load='6hj5' size='340' side='right' caption='[[6hj5]], [[Resolution|resolution]] 2.08Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6hj5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HJ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HJ5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hj5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hj5 OCA], [http://pdbe.org/6hj5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hj5 RCSB], [http://www.ebi.ac.uk/pdbsum/6hj5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hj5 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/GLYC_WWAVU GLYC_WWAVU]] Stable signal peptide (SSP) is cleaved but is apparently retained as the third component of the GP complex. The SSP is required for efficient glycoprotein expression, post-translational cleavage of GP1 and GP2, glycoprotein transport to the cell plasma membrane, formation of infectious virus particles, and acid pH-dependent glycoprotein-mediated cell fusion (By similarity). Glycoprotein G1 mediates virus attachment to host receptor. This interaction leads to virion entry into the host cell through the endosomal pathway (By similarity). Glycoprotein G2 is a class I viral fusion protein, that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm. Membrane fusion is mediated by irreversable conformational changes induced upon acidification in the endosome (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bowden, T A]] | ||
| + | [[Category: Ng, W M]] | ||
| + | [[Category: Omari, K El]] | ||
[[Category: Pryce, R]] | [[Category: Pryce, R]] | ||
[[Category: Wagner, A]] | [[Category: Wagner, A]] | ||
| - | [[Category: Bowden, T.A]] | ||
| - | [[Category: Ng, W.M]] | ||
[[Category: Watanabe, Y]] | [[Category: Watanabe, Y]] | ||
| + | [[Category: Zeltina, A]] | ||
| + | [[Category: Attachment]] | ||
| + | [[Category: Glycoprotein]] | ||
| + | [[Category: Viral protein]] | ||
Revision as of 08:16, 10 October 2018
Crystal structure of Whitewater Arroyo virus GP1 glycoprotein at pH 5.6
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Categories: Bowden, T A | Ng, W M | Omari, K El | Pryce, R | Wagner, A | Watanabe, Y | Zeltina, A | Attachment | Glycoprotein | Viral protein
