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2zbk
From Proteopedia
(Difference between revisions)
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==Crystal structure of an intact type II DNA topoisomerase: insights into DNA transfer mechanisms== | ==Crystal structure of an intact type II DNA topoisomerase: insights into DNA transfer mechanisms== | ||
<StructureSection load='2zbk' size='340' side='right' caption='[[2zbk]], [[Resolution|resolution]] 3.56Å' scene=''> | <StructureSection load='2zbk' size='340' side='right' caption='[[2zbk]], [[Resolution|resolution]] 3.56Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2zbk]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2zbk]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/'saccharolobus_shibatae' 'saccharolobus shibatae']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZBK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ZBK FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RDC:RADICICOL'>RDC</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=RDC:RADICICOL'>RDC</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">top6A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2286 | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">top6A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2286 'Saccharolobus shibatae']), top6B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2286 'Saccharolobus shibatae'])</td></tr> |
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zbk OCA], [http://pdbe.org/2zbk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zbk RCSB], [http://www.ebi.ac.uk/pdbsum/2zbk PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2zbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zbk OCA], [http://pdbe.org/2zbk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zbk RCSB], [http://www.ebi.ac.uk/pdbsum/2zbk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zbk ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zb/2zbk_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zb/2zbk_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Saccharolobus shibatae]] |
[[Category: Cladiere, L]] | [[Category: Cladiere, L]] | ||
[[Category: Durand, D]] | [[Category: Durand, D]] | ||
Revision as of 09:07, 17 October 2018
Crystal structure of an intact type II DNA topoisomerase: insights into DNA transfer mechanisms
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Categories: Saccharolobus shibatae | Cladiere, L | Durand, D | Forterre, P | Graille, M | Lecointe, F | Tilbeurgh, H van | Structural genomic | Atp-binding | Atpase | Decatenation | Dna binding protein | Dna topoisomerase | Dna-binding | Drug design | Isomerase | Magnesium | Metal-binding | Nucleotide-binding | Ysg
