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6bcr
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at T340== | |
| - | + | <StructureSection load='6bcr' size='340' side='right' caption='[[6bcr]], [[Resolution|resolution]] 1.99Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6bcr]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BCR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BCR FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ETF:TRIFLUOROETHANOL'>ETF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |
| - | [[ | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bcr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bcr OCA], [http://pdbe.org/6bcr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bcr RCSB], [http://www.ebi.ac.uk/pdbsum/6bcr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bcr ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/1433T_HUMAN 1433T_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.<ref>PMID:12177059</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Dominguez, R]] | [[Category: Dominguez, R]] | ||
| + | [[Category: Kast, D J]] | ||
| + | [[Category: Cell motility]] | ||
| + | [[Category: Cytoskeleton regulation]] | ||
| + | [[Category: Phosphate binding protein]] | ||
| + | [[Category: Protein complex]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 05:50, 24 October 2018
Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at T340
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