Sialidase

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== Function ==
== Function ==
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'''Salisidase''' is a neuraminidase which cleaves terminal sialic acid from a variety of natural substances <ref>PMID:12374200</ref>.
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'''Salidase''' is a neuraminidase which cleaves terminal sialic acid from a variety of natural substances <ref>PMID:12374200</ref>.
== Disease ==
== Disease ==
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</StructureSection>
</StructureSection>
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==3D structures of salisidase==
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==3D structures of salidase==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
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*Salisidase
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*Salidase
**[[1eur]] - MvNANA residues 43-407 – ''Micromonospora viridifaciens''<br />
**[[1eur]] - MvNANA residues 43-407 – ''Micromonospora viridifaciens''<br />
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**[[2vk5]], [[5tsp]] - CpSal I – ''Clostridium perfringens''<br />
**[[2vk5]], [[5tsp]] - CpSal I – ''Clostridium perfringens''<br />
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*Salisidase complexes
+
*Salidase complexes
**[[2w68]] – VcSal CBD + sialic acid – ''Vibrio cholerae''<br />
**[[2w68]] – VcSal CBD + sialic acid – ''Vibrio cholerae''<br />
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**[[1n1y]]– TrSal + sialic acid <br />
**[[1n1y]]– TrSal + sialic acid <br />
**[[2a75]], [[2fhr]] – TrSal + sialic acid derivative<br />
**[[2a75]], [[2fhr]] – TrSal + sialic acid derivative<br />
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**[[1dim]], [[1dil]], [[2sil]], [[2sim]] – StSal + inhibitor - ''Salmonella typhimurium'' <br />
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**[[1dim]], [[1dil]], [[2sil]], [[2sim]] – StSal + inhibitor <br />
**[[1eus]] - MvSal residues 43-407 + neuraminic acid derivative<br />
**[[1eus]] - MvSal residues 43-407 + neuraminic acid derivative<br />
**[[1eut]] - MvSal residues 47-647 + galactose<br />
**[[1eut]] - MvSal residues 47-647 + galactose<br />
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**[[5mul]] – BtSal + glucuronic acid<br />
**[[5mul]] – BtSal + glucuronic acid<br />
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*'''Trans-sialidase'''
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*Trans-sialidase
 +
 
 +
**[[1mr5]], [[1ms3]], [[1ms4]] - TcSal (mutant) - ''Trypanosoma cruzi''<br />
 +
**[[1ms9]], [[1s0i]], [[3pjq]] - TcSal (mutant) + lactose derivative<br />
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**[[1s0j]], [[2ah2]] - TcSal (mutant) + sialic acid derivative<br />
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**[[3b69]], [[1ms0]], [[1ms1]], [[1ms5]], [[1ms8]] - TcSal (mutant) + neuraminic acid derivative<br />
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**[[3opz]] - TcSal (mutant) + antibody<br />
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**[[1sli]], [[2sli]] - Sal + neuraminic acid derivative - leech<br />
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**[[4x47]] - Sal + neuraminic acid derivative - ''Ruminococcus gnavus''<br />
}}
}}

Revision as of 10:52, 6 November 2018

Caption for this structure

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3D structures of salidase

Updated on 06-November-2018

References

  1. Monti E, Preti A, Venerando B, Borsani G. Recent development in mammalian sialidase molecular biology. Neurochem Res. 2002 Aug;27(7-8):649-63. PMID:12374200

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Jaime Prilusky

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