Colony-stimulating factor

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<StructureSection load='4wrl' size='340' side='right' caption='Caption for this structure' scene=''>
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<StructureSection load='4wrl' size='340' side='right' caption='Glycosylated human macrophage colony-stimulating factor (green and yellow) complex with macrophage colony-stimulating factor 1 receptor (grey and pink) (PDB code [[4wrl]])' scene=''>
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This is a default text for your page '''Colony-stimulating factor'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
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You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
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== Function ==
== Function ==
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*'''Macrophage colony-stimulating factor''' (M-CSF) act on proliferation, functional stimulation and differentiation of progenitors of monocytes and macrophages.<br />
*'''Macrophage colony-stimulating factor''' (M-CSF) act on proliferation, functional stimulation and differentiation of progenitors of monocytes and macrophages.<br />
*'''multi-colony-stimulating factor''' also known as interleukin 3.<br />
*'''multi-colony-stimulating factor''' also known as interleukin 3.<br />
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== Disease ==
 
== Relevance ==
== Relevance ==

Revision as of 07:20, 14 November 2018

Glycosylated human macrophage colony-stimulating factor (green and yellow) complex with macrophage colony-stimulating factor 1 receptor (grey and pink) (PDB code 4wrl)

Drag the structure with the mouse to rotate

3D structures of colony-stimulating factor

Updated on 14-November-2018

References

  1. ↑ Nemunaitis J. A comparative review of colony-stimulating factors. Drugs. 1997 Nov;54(5):709-29. doi: 10.2165/00003495-199754050-00004. PMID:9360058 doi:http://dx.doi.org/10.2165/00003495-199754050-00004
  2. ↑ Shi Y, Liu CH, Roberts AI, Das J, Xu G, Ren G, Zhang Y, Zhang L, Yuan ZR, Tan HS, Das G, Devadas S. Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't know. Cell Res. 2006 Feb;16(2):126-33. doi: 10.1038/sj.cr.7310017. PMID:16474424 doi:http://dx.doi.org/10.1038/sj.cr.7310017
  3. ↑ Hamilton JA. Colony-stimulating factors in inflammation and autoimmunity. Nat Rev Immunol. 2008 Jul;8(7):533-44. doi: 10.1038/nri2356. PMID:18551128 doi:http://dx.doi.org/10.1038/nri2356
  4. ↑ Metcalf D. The colony-stimulating factors and cancer. Nat Rev Cancer. 2010 Jun;10(6):425-34. doi: 10.1038/nrc2843. PMID:20495576 doi:http://dx.doi.org/10.1038/nrc2843
  5. ↑ Schneider A, Kuhn HG, Schabitz WR. A role for G-CSF (granulocyte-colony stimulating factor) in the central nervous system. Cell Cycle. 2005 Dec;4(12):1753-7. doi: 10.4161/cc.4.12.2213. Epub 2005 Dec 27. PMID:16258290 doi:http://dx.doi.org/10.4161/cc.4.12.2213
  6. ↑ Lieschke GJ, Burgess AW. Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor (1). N Engl J Med. 1992 Jul 2;327(1):28-35. doi: 10.1056/NEJM199207023270106. PMID:1375975 doi:http://dx.doi.org/10.1056/NEJM199207023270106

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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