This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5yxk
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==High resolution crystal structure of Human B7-2 IgV domain in P21 space group== | |
| - | + | <StructureSection load='5yxk' size='340' side='right' caption='[[5yxk]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5yxk]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YXK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YXK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yxk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yxk OCA], [http://pdbe.org/5yxk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yxk RCSB], [http://www.ebi.ac.uk/pdbsum/5yxk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yxk ProSAT]</span></td></tr> | |
| - | [[ | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CD86_HUMAN CD86_HUMAN]] Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Lankipalli, S]] | [[Category: Lankipalli, S]] | ||
| - | [[Category: Ramagopal, U | + | [[Category: Ramagopal, U A]] |
| + | [[Category: B7-2]] | ||
| + | [[Category: Cd86]] | ||
| + | [[Category: Co-stimulatory molecule]] | ||
| + | [[Category: Ig super family]] | ||
| + | [[Category: Immune system]] | ||
Revision as of 06:30, 5 December 2018
High resolution crystal structure of Human B7-2 IgV domain in P21 space group
| |||||||||||
