3gbk
From Proteopedia
(Difference between revisions)
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==Crystal Structure of Human PPAR-gamma Ligand Binding Domain Complexed with a Potent and Selective Agonist== | ==Crystal Structure of Human PPAR-gamma Ligand Binding Domain Complexed with a Potent and Selective Agonist== | ||
<StructureSection load='3gbk' size='340' side='right' caption='[[3gbk]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='3gbk' size='340' side='right' caption='[[3gbk]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2PQ:2-[(1-{3-[4-(BIPHENYL-4-YLCARBONYL)-2-PROPYLPHENOXY]PROPYL}-1,2,3,4-TETRAHYDROQUINOLIN-5-YL)OXY]-2-METHYLPROPANOIC+ACID'>2PQ</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2PQ:2-[(1-{3-[4-(BIPHENYL-4-YLCARBONYL)-2-PROPYLPHENOXY]PROPYL}-1,2,3,4-TETRAHYDROQUINOLIN-5-YL)OXY]-2-METHYLPROPANOIC+ACID'>2PQ</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PPAR gamma ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PPAR gamma ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gbk OCA], [http://pdbe.org/3gbk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gbk RCSB], [http://www.ebi.ac.uk/pdbsum/3gbk PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gbk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gbk OCA], [http://pdbe.org/3gbk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gbk RCSB], [http://www.ebi.ac.uk/pdbsum/3gbk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gbk ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gb/3gbk_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gb/3gbk_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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[[Category: Wu, S Y]] | [[Category: Wu, S Y]] | ||
[[Category: Activator]] | [[Category: Activator]] | ||
| + | [[Category: Alternative splicing]] | ||
[[Category: Diabetes mellitus]] | [[Category: Diabetes mellitus]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
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[[Category: Obesity]] | [[Category: Obesity]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| + | [[Category: Polymorphism]] | ||
[[Category: Ppar aganist]] | [[Category: Ppar aganist]] | ||
[[Category: Receptor]] | [[Category: Receptor]] | ||
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[[Category: Type ii diabetes]] | [[Category: Type ii diabetes]] | ||
[[Category: X-ray co-crystal analysis]] | [[Category: X-ray co-crystal analysis]] | ||
| + | [[Category: Zinc]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
Revision as of 06:01, 7 December 2018
Crystal Structure of Human PPAR-gamma Ligand Binding Domain Complexed with a Potent and Selective Agonist
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Categories: Human | Hsieh, H P | Lin, C H | Peng, Y H | Wu, S Y | Activator | Alternative splicing | Diabetes mellitus | Disease mutation | Dna-binding | Ligand binding protein | Metal-binding | Nucleus | Obesity | Phosphoprotein | Polymorphism | Ppar aganist | Receptor | Selective | Structure-based drug design | Transcription | Transcription regulation | Type ii diabetes | X-ray co-crystal analysis | Zinc | Zinc-finger
