7,8-dihydro-8-oxoguanine triphosphatase
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
*<scene name='59/597008/Cv/5'>Active site</scene> of DGTP (PDB code [[3zr0]]).<ref>PMID:21787772</ref> Water molecules are shown as red spheres. | *<scene name='59/597008/Cv/5'>Active site</scene> of DGTP (PDB code [[3zr0]]).<ref>PMID:21787772</ref> Water molecules are shown as red spheres. | ||
| - | *<scene name='59/597008/Cv/ | + | *<scene name='59/597008/Cv/6'>8-oxo-dGTP is located in the tunnel</scene>. |
</StructureSection> | </StructureSection> | ||
Revision as of 12:00, 17 December 2018
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3D structures of 7,8-dihydro-8-oxoguanine triphosphatase
Updated on 17-December-2018
References
- ↑ Nakamura T, Meshitsuka S, Kitagawa S, Abe N, Yamada J, Ishino T, Nakano H, Tsuzuki T, Doi T, Kobayashi Y, Fujii S, Sekiguchi M, Yamagata Y. Structural and dynamic features of the MutT protein in the recognition of nucleotides with the mutagenic 8-oxoguanine base. J Biol Chem. 2010 Jan 1;285(1):444-52. Epub 2009 Oct 28. PMID:19864691 doi:10.1074/jbc.M109.066373
- ↑ Svensson LM, Jemth AS, Desroses M, Loseva O, Helleday T, Hogbom M, Stenmark P. Crystal structure of human MTH1 and the 8-oxo-dGMP product complex. FEBS Lett. 2011 Aug 19;585(16):2617-21. Epub 2011 Jul 23. PMID:21787772 doi:10.1016/j.febslet.2011.07.017
