This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3bpt
From Proteopedia
| Line 4: | Line 4: | ||
|PDB= 3bpt |SIZE=350|CAPTION= <scene name='initialview01'>3bpt</scene>, resolution 1.50Å | |PDB= 3bpt |SIZE=350|CAPTION= <scene name='initialview01'>3bpt</scene>, resolution 1.50Å | ||
|SITE= | |SITE= | ||
| - | |LIGAND= <scene name='pdbligand=QUE:3,5,7,3',4'-PENTAHYDROXYFLAVONE'>QUE</scene> | + | |LIGAND= <scene name='pdbligand=HIU:(2R)-3-HYDROXY-2-METHYLPROPANOIC+ACID'>HIU</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=QUE:3,5,7,3',4'-PENTAHYDROXYFLAVONE'>QUE</scene> |
| - | + | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/3-hydroxyisobutyryl-CoA_hydrolase 3-hydroxyisobutyryl-CoA hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.2.4 3.1.2.4] </span> | |
|GENE= HIBCH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= HIBCH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
| + | |DOMAIN= | ||
| + | |RELATEDENTRY= | ||
| + | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bpt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bpt OCA], [http://www.ebi.ac.uk/pdbsum/3bpt PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3bpt RCSB]</span> | ||
}} | }} | ||
'''Crystal structure of human beta-hydroxyisobutyryl-CoA hydrolase in complex with quercetin''' | '''Crystal structure of human beta-hydroxyisobutyryl-CoA hydrolase in complex with quercetin''' | ||
| + | |||
| + | ==Disease== | ||
| + | Known disease associated with this structure: 3-hydroxyisobutryl-CoA hydrolase deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=610690 610690]] | ||
==About this Structure== | ==About this Structure== | ||
| Line 28: | Line 34: | ||
[[Category: SGC, Structural Genomics Consortium.]] | [[Category: SGC, Structural Genomics Consortium.]] | ||
[[Category: Weigelt, J.]] | [[Category: Weigelt, J.]] | ||
| - | [[Category: HIU]] | ||
| - | [[Category: QUE]] | ||
[[Category: alternative splicing]] | [[Category: alternative splicing]] | ||
[[Category: beta-hydroxyisobutyryl acid]] | [[Category: beta-hydroxyisobutyryl acid]] | ||
| Line 43: | Line 47: | ||
[[Category: transit peptide]] | [[Category: transit peptide]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:28:09 2008'' |
Revision as of 02:28, 31 March 2008
| |||||||
| , resolution 1.50Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , , | ||||||
| Gene: | HIBCH (Homo sapiens) | ||||||
| Activity: | 3-hydroxyisobutyryl-CoA hydrolase, with EC number 3.1.2.4 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of human beta-hydroxyisobutyryl-CoA hydrolase in complex with quercetin
Disease
Known disease associated with this structure: 3-hydroxyisobutryl-CoA hydrolase deficiency OMIM:[610690]
About this Structure
3BPT is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 05:28:09 2008
Categories: 3-hydroxyisobutyryl-CoA hydrolase | Homo sapiens | Single protein | Arrowsmith, C H. | Delft, F von. | Edwards, A M. | Guo, K. | King, O N.F. | Oppermann, U. | Phillips, C. | Pike, A C.W. | Pilka, E S. | SGC, Structural Genomics Consortium. | Weigelt, J. | Alternative splicing | Beta-hydroxyisobutyryl acid | Branched-chain amino acid catabolism | Coenzyme some | Disease mutation | Hydrolase | Mitochondrion | Polymorphism | Quercetin | Sgc | Structural genomics consortium | Transit peptide
