This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6hy5
From Proteopedia
(Difference between revisions)
m (Protected "6hy5" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193C== | |
| - | + | <StructureSection load='6hy5' size='340' side='right' caption='[[6hy5]], [[Resolution|resolution]] 2.58Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6hy5]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HY5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HY5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PLC:DIUNDECYL+PHOSPHATIDYL+CHOLINE'>PLC</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hy5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hy5 OCA], [http://pdbe.org/6hy5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hy5 RCSB], [http://www.ebi.ac.uk/pdbsum/6hy5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hy5 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Delarue, M]] | [[Category: Delarue, M]] | ||
| - | [[Category: Hu, H | + | [[Category: Hu, H D]] |
| + | [[Category: Ion channel]] | ||
| + | [[Category: Lyase]] | ||
| + | [[Category: Pentameric transmembrane channel]] | ||
Revision as of 08:30, 19 December 2018
THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193C
| |||||||||||
