6i8y
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Spindlin1 in complex with the Methyltransferase inhibitor A366== | |
| - | + | <StructureSection load='6i8y' size='340' side='right' caption='[[6i8y]], [[Resolution|resolution]] 1.52Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6i8y]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I8Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I8Y FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2OD:5-METHOXY-6-[3-(PYRROLIDIN-1-YL)PROPOXY]SPIRO[CYCLOBUTANE-1,3-INDOL]-2-AMINE'>2OD</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i8y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i8y OCA], [http://pdbe.org/6i8y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i8y RCSB], [http://www.ebi.ac.uk/pdbsum/6i8y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i8y ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [[http://www.uniprot.org/uniprot/SPIN1_HUMAN SPIN1_HUMAN]] May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Bountra, C]] | ||
| + | [[Category: Burgess-Brown, N A]] | ||
| + | [[Category: Delft, F von]] | ||
| + | [[Category: Edwards, A]] | ||
[[Category: Gileadi, C]] | [[Category: Gileadi, C]] | ||
| - | [[Category: Burgess-Brown, N.A]] | ||
| - | [[Category: Von Delft, F]] | ||
| - | [[Category: Oppermann, U.C.T]] | ||
[[Category: Johansson, C]] | [[Category: Johansson, C]] | ||
| - | [[Category: Edwards, A]] | ||
[[Category: Krojer, T]] | [[Category: Krojer, T]] | ||
| + | [[Category: Oppermann, U C.T]] | ||
| + | [[Category: Shrestha, L]] | ||
| + | [[Category: Sorrell, F J]] | ||
[[Category: Srikannathasan, V]] | [[Category: Srikannathasan, V]] | ||
| - | [[Category: | + | [[Category: Epigenetic]] |
| - | [[Category: | + | [[Category: Gene regulation]] |
| + | [[Category: Methyl-arginine]] | ||
| + | [[Category: Methyl-lysine]] | ||
| + | [[Category: Tudor domain]] | ||
Revision as of 08:24, 26 December 2018
Crystal structure of Spindlin1 in complex with the Methyltransferase inhibitor A366
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