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Arginine repressor

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== Structural highlights ==
== Structural highlights ==
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The structure of ArgR shows a DNA-binding domain at the acidic N-terminal and a basic C-terminal domain which contains the <scene name='55/554907/Cv/5'>intersubunit interaction sites</scene> and the <scene name='55/554907/Cv/7'>Arg binding site</scene>. Every Arg ligand interacts <scene name='55/554907/Cv/9'>with residues from 3 subunits</scene>.<ref>PMID:8594204</ref>
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The structure of ArgR shows a DNA-binding domain at the acidic N-terminal and a basic C-terminal domain which contains the <scene name='55/554907/Cv/5'>intersubunit interaction sites</scene> and the <scene name='55/554907/Cv/10'>Arg binding site</scene>. Every Arg ligand interacts <scene name='55/554907/Cv/11'>with residues from 3 subunits</scene>.<ref>PMID:8594204</ref>
</StructureSection>
</StructureSection>

Revision as of 11:11, 6 January 2019

E. coli structure of arginine repressor C terminal hexamer complex with arginine (PDB entry 1xxb)

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3D structures of arginine repressor

Updated on 06-January-2019

References

  1. Ni J, Sakanyan V, Charlier D, Glansdorff N, Van Duyne GD. Structure of the arginine repressor from Bacillus stearothermophilus. Nat Struct Biol. 1999 May;6(5):427-32. PMID:10331868 doi:http://dx.doi.org/10.1038/8229
  2. Van Duyne GD, Ghosh G, Maas WK, Sigler PB. Structure of the oligomerization and L-arginine binding domain of the arginine repressor of Escherichia coli. J Mol Biol. 1996 Feb 23;256(2):377-91. PMID:8594204 doi:http://dx.doi.org/10.1006/jmbi.1996.0093

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