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452d

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|PDB= 452d |SIZE=350|CAPTION= <scene name='initialview01'>452d</scene>, resolution 1.6&Aring;
|PDB= 452d |SIZE=350|CAPTION= <scene name='initialview01'>452d</scene>, resolution 1.6&Aring;
|SITE=
|SITE=
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|LIGAND= <scene name='pdbligand=9AD:9-AMINO-(N-(2-DIMETHYLAMINO)ETHYL)ACRIDINE-4-CARBOXAMIDE'>9AD</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
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|LIGAND= <scene name='pdbligand=9AD:9-AMINO-(N-(2-DIMETHYLAMINO)ETHYL)ACRIDINE-4-CARBOXAMIDE'>9AD</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
|ACTIVITY=
|ACTIVITY=
|GENE=
|GENE=
 +
|DOMAIN=
 +
|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=452d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=452d OCA], [http://www.ebi.ac.uk/pdbsum/452d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=452d RCSB]</span>
}}
}}
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[[Category: Thorpe, J H.]]
[[Category: Thorpe, J H.]]
[[Category: Todd, A K.]]
[[Category: Todd, A K.]]
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[[Category: 9AD]]
 
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[[Category: MPD]]
 
[[Category: groove binding]]
[[Category: groove binding]]
[[Category: intercalation]]
[[Category: intercalation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:08:25 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:37:23 2008''

Revision as of 02:37, 31 March 2008


PDB ID 452d

Drag the structure with the mouse to rotate
, resolution 1.6Å
Ligands: , , , , ,
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



ACRIDINE BINDING TO DNA


About this Structure

452D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:10052960

Page seeded by OCA on Mon Mar 31 05:37:23 2008

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