3m5u
From Proteopedia
(Difference between revisions)
m (Protected "3m5u" [edit=sysop:move=sysop]) |
|||
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:3m5u.png|left|200px]] | ||
| - | + | ==Crystal Structure of Phosphoserine Aminotransferase from Campylobacter jejuni== | |
| - | + | <StructureSection load='3m5u' size='340' side='right' caption='[[3m5u]], [[Resolution|resolution]] 2.15Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3m5u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"campylobacter_fetus_subsp._jejuni"_smibert_1974 "campylobacter fetus subsp. jejuni" smibert 1974]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3M5U FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr> | |
| - | == | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | [[3m5u]] is a 2 chain structure | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cj0326, serC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=197 "Campylobacter fetus subsp. jejuni" Smibert 1974])</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoserine_transaminase Phosphoserine transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.52 2.6.1.52] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3m5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m5u OCA], [http://pdbe.org/3m5u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3m5u RCSB], [http://www.ebi.ac.uk/pdbsum/3m5u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3m5u ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/SERC_CAMJE SERC_CAMJE]] Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.[HAMAP-Rule:MF_00160] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m5/3m5u_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3m5u ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Phosphoserine aminotransferase|Phosphoserine aminotransferase]] | *[[Phosphoserine aminotransferase|Phosphoserine aminotransferase]] | ||
| - | [[Category: Campylobacter jejuni]] | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Campylobacter fetus subsp. jejuni smibert 1974]] | ||
[[Category: Phosphoserine transaminase]] | [[Category: Phosphoserine transaminase]] | ||
| - | [[Category: Anderson, W F | + | [[Category: Anderson, W F]] |
| - | [[Category: Gu, M | + | [[Category: Structural genomic]] |
| - | [[Category: Joachimiak, A | + | [[Category: Gu, M]] |
| - | [[Category: Kim, Y | + | [[Category: Joachimiak, A]] |
| - | [[Category: Papazisi, L | + | [[Category: Kim, Y]] |
| + | [[Category: Papazisi, L]] | ||
[[Category: Alpha-beta half sandwich]] | [[Category: Alpha-beta half sandwich]] | ||
[[Category: Amino-acid biosynthesis]] | [[Category: Amino-acid biosynthesis]] | ||
[[Category: Aminotransferase]] | [[Category: Aminotransferase]] | ||
| - | [[Category: Center for structural genomics of infectious disease]] | ||
[[Category: Csgid]] | [[Category: Csgid]] | ||
| + | [[Category: Cytoplasm]] | ||
[[Category: Pyridoxal phosphate]] | [[Category: Pyridoxal phosphate]] | ||
[[Category: Pyridoxine biosynthesis]] | [[Category: Pyridoxine biosynthesis]] | ||
[[Category: Serine biosynthesis]] | [[Category: Serine biosynthesis]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Current revision
Crystal Structure of Phosphoserine Aminotransferase from Campylobacter jejuni
| |||||||||||
Categories: Campylobacter fetus subsp. jejuni smibert 1974 | Phosphoserine transaminase | Anderson, W F | Structural genomic | Gu, M | Joachimiak, A | Kim, Y | Papazisi, L | Alpha-beta half sandwich | Amino-acid biosynthesis | Aminotransferase | Csgid | Cytoplasm | Pyridoxal phosphate | Pyridoxine biosynthesis | Serine biosynthesis | Transferase
