This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5h3d
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Helical structure of membrane tubules decorated by ACAP1 (BARPH doamin) protein by cryo-electron microscopy and MD simulation== | |
| - | + | <StructureSection load='5h3d' size='340' side='right' caption='[[5h3d]], [[Resolution|resolution]] 14.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5h3d]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5H3D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5H3D FirstGlance]. <br> | |
| - | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ckg|4ckg]]</td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5h3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5h3d OCA], [http://pdbe.org/5h3d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5h3d RCSB], [http://www.ebi.ac.uk/pdbsum/5h3d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5h3d ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/ACAP1_HUMAN ACAP1_HUMAN]] GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.<ref>PMID:11062263</ref> <ref>PMID:16256741</ref> <ref>PMID:17398097</ref> <ref>PMID:17664335</ref> <ref>PMID:22645133</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chan, C]] | ||
[[Category: Fan, J]] | [[Category: Fan, J]] | ||
| - | [[Category: Pang, X | + | [[Category: Pang, X Y]] |
[[Category: Sun, F]] | [[Category: Sun, F]] | ||
| - | [[Category: | + | [[Category: Zhang, Y]] |
| + | [[Category: Acap1 barph domain]] | ||
| + | [[Category: Membrane remodeling]] | ||
| + | [[Category: Molecular dynamics simulation]] | ||
| + | [[Category: Signaling protein]] | ||
Revision as of 11:57, 16 January 2019
Helical structure of membrane tubules decorated by ACAP1 (BARPH doamin) protein by cryo-electron microscopy and MD simulation
| |||||||||||
