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3n29

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==Crystal structure of carboxynorspermidine decarboxylase complexed with Norspermidine from Campylobacter jejuni==
==Crystal structure of carboxynorspermidine decarboxylase complexed with Norspermidine from Campylobacter jejuni==
<StructureSection load='3n29' size='340' side='right' caption='[[3n29]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3n29' size='340' side='right' caption='[[3n29]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3n29]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_81116 Campylobacter jejuni subsp. jejuni 81116]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N29 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N29 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3n29]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Camj8 Camj8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N29 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N29 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NSD:N-(3-AMINOPROPYL)PROPANE-1,3-DIAMINE'>NSD</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene><br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NSD:N-(3-AMINOPROPYL)PROPANE-1,3-DIAMINE'>NSD</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3n2o|3n2o]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3n2o|3n2o]]</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">carboxynorspermidine decarboxylase, CJJHB9313_1507, nspC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=407148 Campylobacter jejuni subsp. jejuni 81116])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">carboxynorspermidine decarboxylase, CJJHB9313_1507, nspC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=407148 CAMJ8])</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n29 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n29 RCSB], [http://www.ebi.ac.uk/pdbsum/3n29 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n29 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n29 OCA], [http://pdbe.org/3n29 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3n29 RCSB], [http://www.ebi.ac.uk/pdbsum/3n29 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3n29 ProSAT]</span></td></tr>
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<table>
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</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n2/3n29_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n2/3n29_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3n29 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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Evolution of substrate specificity within a diverse family of beta/alpha-barrel-fold basic amino acid decarboxylases: X-ray structure determination of enzymes with specificity for L-arginine and carboxynorspermidine.,Deng X, Lee J, Michael AJ, Tomchick DR, Goldsmith EJ, Phillips MA J Biol Chem. 2010 Aug 13;285(33):25708-19. Epub 2010 Jun 8. PMID:20534592<ref>PMID:20534592</ref>
Evolution of substrate specificity within a diverse family of beta/alpha-barrel-fold basic amino acid decarboxylases: X-ray structure determination of enzymes with specificity for L-arginine and carboxynorspermidine.,Deng X, Lee J, Michael AJ, Tomchick DR, Goldsmith EJ, Phillips MA J Biol Chem. 2010 Aug 13;285(33):25708-19. Epub 2010 Jun 8. PMID:20534592<ref>PMID:20534592</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3n29" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Campylobacter jejuni subsp. jejuni 81116]]
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[[Category: Camj8]]
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[[Category: Deng, X.]]
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[[Category: Deng, X]]
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[[Category: Goldsmith, E J.]]
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[[Category: Goldsmith, E J]]
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[[Category: Lee, J.]]
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[[Category: Lee, J]]
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[[Category: Michael, A J.]]
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[[Category: Michael, A J]]
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[[Category: Phillips, M A.]]
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[[Category: Phillips, M A]]
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[[Category: Tomchick, D R.]]
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[[Category: Tomchick, D R]]
[[Category: Lyase]]
[[Category: Lyase]]

Current revision

Crystal structure of carboxynorspermidine decarboxylase complexed with Norspermidine from Campylobacter jejuni

3n29, resolution 1.90Å

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