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5zym

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'''Unreleased structure'''
 
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The entry 5zym is ON HOLD until Paper Publication
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==Crystal structure of CERT START domain in complex with compound E25B==
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<StructureSection load='5zym' size='340' side='right' caption='[[5zym]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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Authors: Suzuki, M., Nakao, N., Ueno, M., Sakai, S., Egawa, D., Hanzawa, H., Kawasaki, S., Kumagai, K., Kobayashi, S., Hanada, K.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5zym]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZYM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZYM FirstGlance]. <br>
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Description: Crystal structure of CERT START domain in complex with compound E25B
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9M6:2-[4-[4-cyclopentyl-3-[(1~{R},2~{S})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol'>9M6</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5zyg|5zyg]], [[5zyh|5zyh]], [[5zyi|5zyi]], [[5zyj|5zyj]], [[5zyk|5zyk]], [[5zyl|5zyl]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zym OCA], [http://pdbe.org/5zym PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zym RCSB], [http://www.ebi.ac.uk/pdbsum/5zym PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zym ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/C43BP_HUMAN C43BP_HUMAN]] Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.<ref>PMID:14685229</ref> <ref>PMID:17591919</ref> <ref>PMID:18184806</ref> <ref>PMID:20036255</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Egawa, D]]
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[[Category: Hanada, K]]
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[[Category: Hanzawa, H]]
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[[Category: Kawasaki, S]]
[[Category: Kobayashi, S]]
[[Category: Kobayashi, S]]
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[[Category: Hanada, K]]
 
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[[Category: Suzuki, M]]
 
[[Category: Kumagai, K]]
[[Category: Kumagai, K]]
[[Category: Nakao, N]]
[[Category: Nakao, N]]
[[Category: Sakai, S]]
[[Category: Sakai, S]]
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[[Category: Egawa, D]]
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[[Category: Suzuki, M]]
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[[Category: Hanzawa, H]]
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[[Category: Kawasaki, S]]
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[[Category: Ueno, M]]
[[Category: Ueno, M]]
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[[Category: Cert]]
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[[Category: Complex]]
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[[Category: Lipid transport]]
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[[Category: Ph]]
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[[Category: Start]]

Revision as of 15:13, 27 February 2019

Crystal structure of CERT START domain in complex with compound E25B

5zym, resolution 1.90Å

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