Alanine racemase
From Proteopedia
(Difference between revisions)
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AR uses 2 catalytic bases for the reaction: <scene name='55/551209/Cv/3'>Lys and Tyr</scene> from different monomers.<ref name="Ad">PMID:11886871</ref> Water molecules are shown as red spheres. <scene name='55/551209/Cv/5'>Whole active site</scene>. | AR uses 2 catalytic bases for the reaction: <scene name='55/551209/Cv/3'>Lys and Tyr</scene> from different monomers.<ref name="Ad">PMID:11886871</ref> Water molecules are shown as red spheres. <scene name='55/551209/Cv/5'>Whole active site</scene>. | ||
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| + | == 3D Structures of alanine racemase == | ||
| + | [[Alanine racemase 3D structures]] | ||
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</StructureSection> | </StructureSection> | ||
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**[[3uw6]] – GsAR – ''Geobacillus stearothermophilus'' <BR /> | **[[3uw6]] – GsAR – ''Geobacillus stearothermophilus'' <BR /> | ||
**[[3hur]] – OoAR - ''Oenococcus oeni''<BR /> | **[[3hur]] – OoAR - ''Oenococcus oeni''<BR /> | ||
| - | **[[3oo2]] – SaAR - ''Staphyloococcus aureus''<BR /> | + | **[[3oo2]], [[6g56]] – SaAR - ''Staphyloococcus aureus''<BR /> |
**[[4bhy]] – AhAR – ''Aeromonas hydrophila''<br /> | **[[4bhy]] – AhAR – ''Aeromonas hydrophila''<br /> | ||
**[[3c3k]] – AR – ''Actinobacillus succinogenes''<br /> | **[[3c3k]] – AR – ''Actinobacillus succinogenes''<br /> | ||
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**[[1xfc]] – AR + PLP – ''Mycobacterium tuberculosis'' <BR /> | **[[1xfc]] – AR + PLP – ''Mycobacterium tuberculosis'' <BR /> | ||
**[[2dy3]] – AR + PLP – ''Corynebacterium glutamicum'' <BR /> | **[[2dy3]] – AR + PLP – ''Corynebacterium glutamicum'' <BR /> | ||
| + | **[[5yyc]] – AR + PLP – ''Bacillus pseudofirmus'' <BR /> | ||
**[[3ha1]] – BaAR + lysine-PLP <BR /> | **[[3ha1]] – BaAR + lysine-PLP <BR /> | ||
**[[3kw3]] – AR + lysine-PLP - ''Bartonella henselae''<BR /> | **[[3kw3]] – AR + lysine-PLP - ''Bartonella henselae''<BR /> | ||
**[[3s46]] – AR + lysine-PLP - ''Streptococcus pneumoniae''<BR /> | **[[3s46]] – AR + lysine-PLP - ''Streptococcus pneumoniae''<BR /> | ||
| - | **[[1rcq]] – AR + | + | **[[1rcq]], [[6a2f]] – AR + PLP derivative - ''Pseudomonas aeruginosa''<BR /> |
**[[2odo]] – AR + lysine-PLP - ''Pseudomonas fluorescens''<BR /> | **[[2odo]] – AR + lysine-PLP - ''Pseudomonas fluorescens''<BR /> | ||
**[[2rjg]] – EcAR + PLP <BR /> | **[[2rjg]] – EcAR + PLP <BR /> | ||
**[[3b8t]], [[3b8u]], [[3b8v]], [[3b8w]], [[4wr3]] – EcAR (mutant) + PLP<br /> | **[[3b8t]], [[3b8u]], [[3b8v]], [[3b8w]], [[4wr3]] – EcAR (mutant) + PLP<br /> | ||
**[[3co8]] – OoAR + PLP <BR /> | **[[3co8]] – OoAR + PLP <BR /> | ||
| - | **[[4a3q]] – SaAR + PLP | + | **[[4a3q]], [[6g58]], [[6g59]] – SaAR + PLP derivative <BR /> |
**[[3e5p]] – EfAR + PLP - ''Enterococcus faecalis''<BR /> | **[[3e5p]] – EfAR + PLP - ''Enterococcus faecalis''<BR /> | ||
**[[4beu]] – VcAR + PLP – ''Vibrio cholerae''<br /> | **[[4beu]] – VcAR + PLP – ''Vibrio cholerae''<br /> | ||
Revision as of 11:26, 3 March 2019
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3D Structures of alanine racemase
Updated on 03-March-2019
References
- ↑ 1.0 1.1 Watanabe A, Yoshimura T, Mikami B, Hayashi H, Kagamiyama H, Esaki N. Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine. J Biol Chem. 2002 May 24;277(21):19166-72. Epub 2002 Mar 8. PMID:11886871 doi:10.1074/jbc.M201615200
