6h2x
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==MukB coiled-coil elbow from E. coli== | |
| - | + | <StructureSection load='6h2x' size='340' side='right' caption='[[6h2x]], [[Resolution|resolution]] 2.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6h2x]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H2X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6H2X FirstGlance]. <br> | |
| - | + | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6h2x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h2x OCA], [http://pdbe.org/6h2x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6h2x RCSB], [http://www.ebi.ac.uk/pdbsum/6h2x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6h2x ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/MUKB_ECOLI MUKB_ECOLI]] Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organizes and compacts chromosomes. May achieve or facilitate chromosome segregation by condensation of DNA from both sides of a centrally located replisome during cell division. Stimulates both DNA relaxation and to a lesser extent decatenation activity of topoisomerase IV.<ref>PMID:20921377</ref> <ref>PMID:10660686</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Buermann, F]] | ||
| + | [[Category: Lowe, J]] | ||
| + | [[Category: Chromosome organization]] | ||
| + | [[Category: Chromosome segregation]] | ||
| + | [[Category: Coiled coil]] | ||
| + | [[Category: Dna binding protein]] | ||
Revision as of 07:29, 6 March 2019
MukB coiled-coil elbow from E. coli
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