Alpha-lytic protease

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*<scene name='55/551214/Cv/4'>ALP protease domain and pro domain complex with benzenesulfonyl fluoride</scene>. Water molecules are shown as red spheres.
*<scene name='55/551214/Cv/4'>ALP protease domain and pro domain complex with benzenesulfonyl fluoride</scene>. Water molecules are shown as red spheres.
*<scene name='55/551214/Cv/5'>Benzenesulfonyl fluoride binding site</scene> (PDB entry [[3pro]]).<ref>PMID:9808037</ref>
*<scene name='55/551214/Cv/5'>Benzenesulfonyl fluoride binding site</scene> (PDB entry [[3pro]]).<ref>PMID:9808037</ref>
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</StructureSection>
 
== 3D Structures of alpha-lytic protease ==
== 3D Structures of alpha-lytic protease ==
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[[Alpha-lytic protease 3D structures]]
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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</StructureSection>
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{{#tree:id=OrganizedByTopic|openlevels=0|
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*ALP protease domain
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**[[2alp]], [[1p09]], [[1tal]], [[2ull]], [[1boq]], [[1ssz]], [[2h5c]], [[1ssx]] – LeALP – ''Lysobacter enzymogenes'' <BR />
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**[[1gba]], [[1gbe]], [[1gbj]], [[3urc]], [[3urd]], [[3ure]], [[1qq4]] – LeALP (mutant) <BR />
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**[[5wot]] – LeALP - NMR <BR />
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**[[1p01]], [[1p02]], [[1p03]], [[1p04]], [[1p05]], [[1p06]], [[1p10]], [[2lpr]], [[3lpr]], [[5lpr]], [[6lpr]], [[7lpr]], [[8lpr]], [[9lpr]], [[2h5d]] – LeALP + boronic acid inhibitor <BR />
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**[[1gbb]], [[1gbc]], [[1gbd]], [[1gbf]], [[1gbh]], [[1gbi]], [[1gbk]], [[1gbl]], [[1gbm]] – LeALP (mutant) + boronic acid inhibitor <BR />
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**[[1p11]], [[1p12]] – LeALP + phosphonate esther inhibitor <BR />
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**[[3qgj]] – LeALP + peptide <BR />
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*ALP pro region
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**[[2pro]], [[1qrx]] – LeALP pro region <BR />
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**[[1qrw]], [[3m7t]], [[3m7u]] – LeALP pro region (mutant) <BR />
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*ALP pro+protease domains
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**[[3pro]], [[4pro]] – LeALP (mutant) <BR />
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category: Topic Page]]
[[Category: Topic Page]]

Current revision

Structure of alpha-lytic protease protease domain (green) and pro domain (magenta) complex with benzenesulfonyl fluoride (PDB entry 3pro)

Drag the structure with the mouse to rotate

References

  1. ↑ Bone R, Frank D, Kettner CA, Agard DA. Structural analysis of specificity: alpha-lytic protease complexes with analogues of reaction intermediates. Biochemistry. 1989 Sep 19;28(19):7600-9. PMID:2611204
  2. ↑ Sauter NK, Mau T, Rader SD, Agard DA. Structure of alpha-lytic protease complexed with its pro region. Nat Struct Biol. 1998 Nov;5(11):945-50. PMID:9808037 doi:http://dx.doi.org/10.1038/2919

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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