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6q5b
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==OXA-48_P68A-AVI. Evolutionary trade-offs of OXA-48 mediated ceftazidime-avibactam resistance== | |
| - | + | <StructureSection load='6q5b' size='340' side='right'caption='[[6q5b]], [[Resolution|resolution]] 2.22Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6q5b]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Q5B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Q5B FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO2:CARBON+DIOXIDE'>CO2</scene>, <scene name='pdbligand=NXL:(2S,5R)-1-FORMYL-5-[(SULFOOXY)AMINO]PIPERIDINE-2-CARBOXAMIDE'>NXL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr> |
| - | [[Category: Leiros, H | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6q5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6q5b OCA], [http://pdbe.org/6q5b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6q5b RCSB], [http://www.ebi.ac.uk/pdbsum/6q5b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6q5b ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Beta-lactamase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Frohlich, C]] | ||
| + | [[Category: Johnsen, P J]] | ||
| + | [[Category: Leiros, H K.S]] | ||
[[Category: Samuelsen, O]] | [[Category: Samuelsen, O]] | ||
| - | [[Category: Frohlich, C]] | ||
[[Category: Sorum, V]] | [[Category: Sorum, V]] | ||
| - | [[Category: | + | [[Category: Thomassen, A M]] |
| - | [[Category: | + | [[Category: Antibiotic]] |
| + | [[Category: Avibactam]] | ||
| + | [[Category: Carbapenem]] | ||
| + | [[Category: Carbapenemase]] | ||
| + | [[Category: Ceftazidime]] | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Evolution]] | ||
| + | [[Category: Klebsiella pneumoniae]] | ||
| + | [[Category: Oxa-48]] | ||
| + | [[Category: Resistance development]] | ||
Revision as of 08:07, 20 March 2019
OXA-48_P68A-AVI. Evolutionary trade-offs of OXA-48 mediated ceftazidime-avibactam resistance
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