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4cva

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==MPS1 kinase with 3-aminopyridin-2-one inhibitors==
==MPS1 kinase with 3-aminopyridin-2-one inhibitors==
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<StructureSection load='4cva' size='340' side='right' caption='[[4cva]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='4cva' size='340' side='right'caption='[[4cva]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4cva]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CVA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4cva]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CVA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=WBI:N-(6-OXO-1,6-DIHYDRO-3,4-BIPYRIDIN-5-YL)-4-(PIPERIDIN-1-YL)BENZAMIDE'>WBI</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=WBI:N-(6-OXO-1,6-DIHYDRO-3,4-BIPYRIDIN-5-YL)-4-(PIPERIDIN-1-YL)BENZAMIDE'>WBI</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
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</StructureSection>
</StructureSection>
[[Category: Dual-specificity kinase]]
[[Category: Dual-specificity kinase]]
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Bavetsias, V]]
[[Category: Bavetsias, V]]
[[Category: Bayliss, R]]
[[Category: Bayliss, R]]

Revision as of 09:16, 20 March 2019

MPS1 kinase with 3-aminopyridin-2-one inhibitors

PDB ID 4cva

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