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Barstar

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[[Image:2hxx.png|left|200px|thumb|Crystal Structure of Barstar [[2hxx]]]]
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<StructureSection load='1a19' size='450' side='right' scene='44/442747/Cv/2' caption='Barstar dimer [[1a19]]'>
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{{STRUCTURE_2hxx| PDB=2hxx | SIZE=300| SCENE=Barstar/Cv/1 |right|CAPTION=Barstar [[2hxx]] }}
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'''Barstar''' (BST) is an inhibitor synthesized and secreted by the bacterium ''Bacillus amyloliquefaciens''. It binds to the ribonuclease barnase (BA) very tightly and prevents it from digestion of the cell’s RNA.<ref>PMID:8043575</ref>
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'''Barstar''' (BST) is an inhibitor synthesized and secreted by the bacterium ''Bacillus amyloliquefaciens''. It binds to the ribonuclease barnase (BA) very tightly and prevents it from digestion of the cell’s RNA.
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{{TOC limit|limit=2}}
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== 3D Structures of Barstar ==
== 3D Structures of Barstar ==
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[[Barstar 3D structures]]
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[[2hxx]], [[2cx6]] – BST<br />
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</StructureSection>
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[[1a19]] – BST (mutant)<br />
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[[1l1k]], [[1bta]], [[1btb]] – BST – NMR<br />
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[[1ab7]] - BST (mutant) - NMR
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===BST + BA===
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[[3da7]] – BST + BA (mutant) <br />
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[[2za4]], [[1brs]], [[1bgs]] – BST + BA <br />
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[[1x1u]], [[1x1w]], [[1x1x]], [[1x1y]], [[1b27]], [[1b2u]] – BST (mutant) + BA<br />
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[[1b3s]], [[1b2s]] - BST (mutant) + BA (mutant)<br />
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[[1ay7]] – BST + guanyl-specific RNase SA – ''Streptomyces aureofaciens''
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== References ==
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<references/>
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[[Category:Topic Page]]

Current revision

Barstar dimer 1a19

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References

  1. ↑ Buckle AM, Schreiber G, Fersht AR. Protein-protein recognition: crystal structural analysis of a barnase-barstar complex at 2.0-A resolution. Biochemistry. 1994 Aug 2;33(30):8878-89. PMID:8043575

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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