5zxk
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with HMBPP== | |
| - | + | <StructureSection load='5zxk' size='340' side='right'caption='[[5zxk]], [[Resolution|resolution]] 1.96Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5zxk]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZXK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZXK FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H6P:(2E)-4-HYDROXY-3-METHYLBUT-2-EN-1-YL+TRIHYDROGEN+DIPHOSPHATE'>H6P</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zxk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zxk OCA], [http://pdbe.org/5zxk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zxk RCSB], [http://www.ebi.ac.uk/pdbsum/5zxk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zxk ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BT3A1_HUMAN BT3A1_HUMAN]] Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.<ref>PMID:21113407</ref> <ref>PMID:21918970</ref> <ref>PMID:22767497</ref> <ref>PMID:22846996</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen, C C]] | ||
| + | [[Category: Guo, R T]] | ||
| + | [[Category: Liu, W D]] | ||
| + | [[Category: Yang, Y Y]] | ||
| + | [[Category: Zhang, Y H]] | ||
| + | [[Category: Agonist]] | ||
| + | [[Category: Signaling protein]] | ||
| + | [[Category: Substrate binding]] | ||
Revision as of 06:49, 3 April 2019
Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with HMBPP
| |||||||||||
