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6j06

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'''Unreleased structure'''
 
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The entry 6j06 is ON HOLD until Paper Publication
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==Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with HMBPP-08==
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<StructureSection load='6j06' size='340' side='right'caption='[[6j06]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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Authors: Yang, Y.Y., Liu, W.D., Cai, N.N., Chen, C.C., Guo, R.T., Zhang, Y.H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6j06]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J06 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6J06 FirstGlance]. <br>
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Description: Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with THZ-526
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=99C:(2E)-3-(hydroxymethyl)-4-(4-methylphenyl)but-2-en-1-yl+trihydrogen+diphosphate'>99C</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6j06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j06 OCA], [http://pdbe.org/6j06 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6j06 RCSB], [http://www.ebi.ac.uk/pdbsum/6j06 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6j06 ProSAT]</span></td></tr>
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[[Category: Chen, C.C]]
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</table>
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[[Category: Liu, W.D]]
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== Function ==
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[[Category: Zhang, Y.H]]
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[[http://www.uniprot.org/uniprot/BT3A1_HUMAN BT3A1_HUMAN]] Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.<ref>PMID:21113407</ref> <ref>PMID:21918970</ref> <ref>PMID:22767497</ref> <ref>PMID:22846996</ref>
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[[Category: Guo, R.T]]
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== References ==
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[[Category: Cai, N.N]]
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<references/>
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[[Category: Yang, Y.Y]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Cai, N N]]
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[[Category: Chen, C C]]
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[[Category: Guo, R T]]
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[[Category: Liu, W D]]
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[[Category: Yang, Y Y]]
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[[Category: Zhang, Y H]]
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[[Category: Butyrophilin]]
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[[Category: Signaling protein]]

Revision as of 07:03, 3 April 2019

Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with HMBPP-08

PDB ID 6j06

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