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Beta-2 microglobulin
From Proteopedia
(Difference between revisions)
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== Structural Highlights == | == Structural Highlights == | ||
<scene name='45/459284/Cv/2'>Human β-2 microglobulin with MHC class I HLA-A2 and HCMV PP65 nonapeptide</scene> ([[3mrb]]). | <scene name='45/459284/Cv/2'>Human β-2 microglobulin with MHC class I HLA-A2 and HCMV PP65 nonapeptide</scene> ([[3mrb]]). | ||
| + | |||
| + | == 3D Structures of β-2 microglobulin == | ||
| + | [[Beta-2 microglobulin 3D structures]] | ||
| + | |||
</StructureSection> | </StructureSection> | ||
== 3D Structures of β-2 microglobulin == | == 3D Structures of β-2 microglobulin == | ||
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**[[2e8d]] - hβ-2-microglobulin residues 40-61 - NMR<BR /> | **[[2e8d]] - hβ-2-microglobulin residues 40-61 - NMR<BR /> | ||
**[[3low]], [[2yxf]], [[2d4f]], [[1lds]] - hβ-2-microglobulin<BR /> | **[[3low]], [[2yxf]], [[2d4f]], [[1lds]] - hβ-2-microglobulin<BR /> | ||
| + | **[[6gk3]] - hβ-2-microglobulin – Cryo EM<br /> | ||
**[[3gbl]] - gcβ-2-microglobulin residues 1-97 - grass carp<BR /> | **[[3gbl]] - gcβ-2-microglobulin residues 1-97 - grass carp<BR /> | ||
**[[1bmg]] - bβ-2-microglobulin - bovine<br /> | **[[1bmg]] - bβ-2-microglobulin - bovine<br /> | ||
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**[[4ono]] - hβ-2-microglobulin/CD1C/CD1B<br /> | **[[4ono]] - hβ-2-microglobulin/CD1C/CD1B<br /> | ||
**[[4x6e]], [[5j1a]] - hβ-2-microglobulin + CD1A<br /> | **[[4x6e]], [[5j1a]] - hβ-2-microglobulin + CD1A<br /> | ||
| - | **[[3t8x]], [[5l2j]], [[5wl1]], [[5wkg]], [[5wke]] - hβ-2-microglobulin + hCD1B<br /> | + | **[[3t8x]], [[5l2j]], [[5wl1]], [[5wkg]], [[5wke]], [[6d64]] - hβ-2-microglobulin + hCD1B<br /> |
| - | **[[5wki]] - | + | **[[5wki]] - hβ-2-microglobulin + CD1B + TCR<br /> |
**[[5c9j]] - hβ-2-microglobulin + CD1C<br /> | **[[5c9j]] - hβ-2-microglobulin + CD1C<br /> | ||
| - | **[[6c15]] - | + | **[[6c15]] - hβ-2-microglobulin + CD1C + phosphatidylcholine<br /> |
| - | **[[6c09]] - | + | **[[6c09]] - hβ-2-microglobulin + CD1C + TCR<br /> |
**[[3u0p]] - hβ-2-microglobulin + hCD1D (mutant)<br /> | **[[3u0p]] - hβ-2-microglobulin + hCD1D (mutant)<br /> | ||
**[[3ma7]], [[3ilp]], [[3ilq]], [[3g08]], [[3gml]], [[3gmm]], [[3gmn]], [[3gmo]], [[3gmp]], [[3gmq]], [[3gmr]], [[1zhn]], [[3t1f]], [[4mq7]], [[4mx7]] - mβ-2-microglobulin + CD1D1<BR /> | **[[3ma7]], [[3ilp]], [[3ilq]], [[3g08]], [[3gml]], [[3gmm]], [[3gmn]], [[3gmo]], [[3gmp]], [[3gmq]], [[3gmr]], [[1zhn]], [[3t1f]], [[4mq7]], [[4mx7]] - mβ-2-microglobulin + CD1D1<BR /> | ||
**[[2gaz]], [[2fik]], [[1z5l]], [[3au1]] - mβ-2-microglobulin + CD1D1 extracellular domain<BR /> | **[[2gaz]], [[2fik]], [[1z5l]], [[3au1]] - mβ-2-microglobulin + CD1D1 extracellular domain<BR /> | ||
| - | **[[2akr]] - mβ-2-microglobulin residues 21-119+ CD1D1 extracellular domain<BR /> | + | **[[2akr]], [[6c6j]], [[6c6h]], [[6c6f]], [[6c6e]], [[6c6c]], [[6c6a]], [[6c69]], [[6c5m]] - mβ-2-microglobulin residues 21-119+ CD1D1 extracellular domain<BR /> |
| - | **[[6bmk]], [[6bmh]] - | + | **[[6bnl]], [[6bnk]] - mβ-2-microglobulin residues 21-119+ CD1D1 extracellular domain + TCR<br /> |
| + | **[[6bmk]], [[6bmh]] - mβ-2-microglobulin + CD1D2<br /> | ||
**[[4f7c]], [[4f7e]] - bβ-2-microglobulin + CD1D<br /> | **[[4f7c]], [[4f7e]] - bβ-2-microglobulin + CD1D<br /> | ||
**[[2h26]] - hβ-2-microglobulin + CD1B extracellular domain<BR /> | **[[2h26]] - hβ-2-microglobulin + CD1B extracellular domain<BR /> | ||
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**[[1pqz]] - mβ-2-microglobulin + MCMV M144<br /> | **[[1pqz]] - mβ-2-microglobulin + MCMV M144<br /> | ||
**[[4iiq]], [[4l8s]], [[4l9l]], [[4lcc]], [[4lcw]] - bβ-2-microglobulin + Tc receptor<br /> | **[[4iiq]], [[4l8s]], [[4l9l]], [[4lcc]], [[4lcw]] - bβ-2-microglobulin + Tc receptor<br /> | ||
| + | **[[6c99]], [[6c98]], [[6c97]] - hβ-2-microglobulin + Igg receptor P51<br /> | ||
| + | **[[6a97]] - hβ-2-microglobulin + MILL2<br /> | ||
*B2M in ternary complex with MHC | *B2M in ternary complex with MHC | ||
| - | **[[4d0b]], [[3bew]], [[4e0r]], [[4g42]], [[4g43]] – cβ-2-microglobulin + cMHC I α + peptide<br /> | + | **[[4d0b]], [[3bew]], [[4e0r]], [[4g42]], [[4g43]], [[5ymw]], [[5ymv]] – cβ-2-microglobulin + cMHC I α + peptide<br /> |
**[[2xfx]] - bβ-2-microglobulin + MHC I α + peptide<br /> | **[[2xfx]] - bβ-2-microglobulin + MHC I α + peptide<br /> | ||
**[[3jts]], [[3jtt]], [[1zvs]], [[3rwc]], [[3rwd]], [[3rwe]], [[3rwf]], [[3rwg]], [[3rwh]], [[3rwi]], [[3rwj]] - β-2-microglobulin + MHC I α + peptide – Macaca mulatta<BR /> | **[[3jts]], [[3jtt]], [[1zvs]], [[3rwc]], [[3rwd]], [[3rwe]], [[3rwf]], [[3rwg]], [[3rwh]], [[3rwi]], [[3rwj]] - β-2-microglobulin + MHC I α + peptide – Macaca mulatta<BR /> | ||
**[[3kpn]], [[3kpo]] – hβ-2-microglobulin + hMHC I B + peptide<br /> | **[[3kpn]], [[3kpo]] – hβ-2-microglobulin + hMHC I B + peptide<br /> | ||
| - | **[[3bev]], [[1kpr]], [[1k5n]], [[3nfn]], [[3mr9]], [[3mrb]], [[3mrc]], [[3mrd]], [[3mre]], [[3mrf]], [[3mrg]], [[3mrh]], [[3mri]], [[3mrj]], [[3mrk]], [[3mrl]], [[3mrm]], [[3mrn]], [[3mro]], [[3mrp]], [[3mrq]], [[3mrr]], [[3ox8]], [[3oxr]], [[3oxs]], [[2xpg]], [[3pwj]], [[3pwl]], [[3pwn]], [[3pwp]], [[2x70]], [[3o3a]], [[3o3b]], [[3o3d]], [[3o3e]], [[3lv3]], [[3ln4]], [[3ln5]], [[3myj]], [[3i6l]], [[3lkn]], [[3lko]], [[3lkp]], [[3lkq]], [[3lkr]], [[3lks]], [[3hpj]], [[3i6g]], [[3i6k]], [[3mgo]], [[3mgt]], [[3l3d]], [[3l3g]], [[3l3h]], [[3l3i]], [[3l3j]], [[3l3k]], [[2x4n]], [[2x4o]], [[2x4p]], [[2x4q]], [[2x4r]], [[2x4s]], [[2x4t]], [[2x4u]], [[3lka]], [[3h7b]], [[3kpl]], [[3kpm]], [[3kpn]], [[3kpo]], [[3kpp]], [[3kpq]], [[3kpr]], [[3kps]], [[3giv]], [[3hcv]], [[3d18]], [[3dtx]], [[3czf]], [[3fqn]], [[3fqr]], [[3fqt]], [[3fqu]], [[3fqw]], [[3fqx]], [[3d25]], [[3bvn]], [[3dx6]], [[3dx7]], [[3dx8]], [[3dxa]], [[3bo8]], [[3bp4]], [[3bp7]], [[3bgm]], [[3bh8]], [[3bh9]], [[3bhb]], [[3b3i]], [[3b6s]], [[2rfx]], [[3bze]], [[3bzf]], [[3bw9]], [[3bwa]], [[3c9n]], [[2v2w]], [[2v2x]], [[2gt9]], [[2gtw]], [[2gtz]], [[2guo]], [[2nw3]], [[2fyy]], [[2fz3]], [[2hn7]], [[2cik]], [[2git]], [[2hjk]], [[2hjl]], [[2h6p]], [[2d31]], [[2c7u]], [[2bck]], [[2a83]], [[2axf]], [[2axg]], [[2bvo]], [[2bvp]], [[2bvq]], [[1s8d]], [[1t1w]], [[1t1x]], [[1t1y]], [[1t1z]], [[1t20]], [[1t21]], [[1t22]], [[1s7q]], [[1zsd]], [[2bsr]], [[2bss]], [[2bst]], [[1zhk]], [[1zhl]], [[1tvb]], [[1tvh]], [[1xr8]], [[1xr9]], [[1w0v]], [[1w0w]], [[1xh3]], [[1uxs]], [[1uxw]], [[1s9w]], [[1s9x]], [[1s9y]], [[1q94]], [[1qvo]], [[1n2r]], [[1ogt]], [[1qew]], [[1jge]], [[1k5n]], [[1i7r]], [[1i7t]], [[1i7u]], [[1jf1]], [[1jht]], [[1i4f]], [[1e27]], [[1e28]], [[1i1y]], [[1i1f]], [[1qqd]], [[1mhe]], [[1b0g]], [[1a9b]], [[1a9e]], [[1a1m]], [[1a1n]], [[1a1o]], [[1tmc]], [[2clr]], [[1hhg]], [[1hhh]], [[1hhi]], [[1hhj]], [[1hhk]], [[1hsb]], [[1hsa]], [[3kla]], [[3giv]], [[3d18]], [[3bxn]], [[1x7q]], [[1ydp]], [[1sys]], [[1of2]], [[1jgd]], [[1eey]], [[1eez]], [[1duy]], [[1duz]], [[1agb]], [[1agc]], [[1agd]], [[1age]], [[1agf]], [[3am8]], [[3qfd]], [[3rew]], [[3rl1]], [[3rl2]], [[3skm]], [[3sko]], [[3utq]], [[3uts]], [[3utt]], [[3vfm]], [[3vfn]], [[3vfo]], [[3vfp]], [[3vfr]], [[3vfs]], [[3vft]], [[3vfu]], [[3vfv]], [[3vfw]], [[3vh8]], [[2ypk]], [[3spv]], [[3tid]], [[3tie]], [[3to2]], [[3upr]], [[3v5d]], [[3v5h]], [[3v5k]], [[3vcl]], [[3vri]], [[3vrj]], [[4f7m]], [[4f7p]], [[4f7t]], [[4gks]], [[4i4w]], [[3w39]], [[4g8i]], [[4g9d]], [[4jqv]], [[4jqx]], [[4k7f]], [[1b0r]], [[3vxm]], [[3vxn]], [[3vxo]], [[3vxp]], [[3vxr]], [[3vxs]], [[3vxu]], [[3w0w]], [[4hwz]], [[4hx1]], [[4i48]], [[4nqv]], [[4nqx]], [[3wl9]], [[3wlb]], [[3ws3]], [[3ws6]], [[3x11]], [[3x12]], [[3x13]], [[3x14]], [[4hs3]], [[4lcy]], [[4lnr]], [[4mj5]], [[4mj6]], [[4nnx]], [[4nny]], [[4no2]], [[4no3]], [[4no5]], [[4nt6]], [[4o2c]], [[4o2e]], [[4o2f]], [[4pr5]], [[4pra]], [[4prb]], [[4prd]], [[4pre]], [[4prn]], [[4qrq]], [[4qrs]], [[4qrt]], [[4qru]], [[4u6x]], [[4u6y]], [[4uq2]], [[4uq3]], [[4wj5]], [[6ei2]], [[6bxp]], [[6at9]], [[6at5]], [[5xos]], [[5wxd]], [[5wxc]], [[5wwu]], [[5wwj]], [[5wwi]], [[5wsh]], [[5wjn]], [[5wjl]], [[5w6a]], [[5w69]], [[5w67]], [[5vz5]], [[5vge]], [[5vgd]], [[5v5m]], [[5v5l]], [[5u98]], [[5txs]], [[5opi]], [[5nmk]], [[5nmh]], [[5n6b]], [[5iue]], [[5gsx]], [[5gsv]], [[5gsr]], [[5gsd]], [[5gsb]], [[5grg]], [[5grd]], [[5gr7]] - hβ-2-microglobulin + hMHC I α + peptide<br /> | + | **[[3bev]], [[1kpr]], [[1k5n]], [[3nfn]], [[3mr9]], [[3mrb]], [[3mrc]], [[3mrd]], [[3mre]], [[3mrf]], [[3mrg]], [[3mrh]], [[3mri]], [[3mrj]], [[3mrk]], [[3mrl]], [[3mrm]], [[3mrn]], [[3mro]], [[3mrp]], [[3mrq]], [[3mrr]], [[3ox8]], [[3oxr]], [[3oxs]], [[2xpg]], [[3pwj]], [[3pwl]], [[3pwn]], [[3pwp]], [[2x70]], [[3o3a]], [[3o3b]], [[3o3d]], [[3o3e]], [[3lv3]], [[3ln4]], [[3ln5]], [[3myj]], [[3i6l]], [[3lkn]], [[3lko]], [[3lkp]], [[3lkq]], [[3lkr]], [[3lks]], [[3hpj]], [[3i6g]], [[3i6k]], [[3mgo]], [[3mgt]], [[3l3d]], [[3l3g]], [[3l3h]], [[3l3i]], [[3l3j]], [[3l3k]], [[2x4n]], [[2x4o]], [[2x4p]], [[2x4q]], [[2x4r]], [[2x4s]], [[2x4t]], [[2x4u]], [[3lka]], [[3h7b]], [[3kpl]], [[3kpm]], [[3kpn]], [[3kpo]], [[3kpp]], [[3kpq]], [[3kpr]], [[3kps]], [[3giv]], [[3hcv]], [[3d18]], [[3dtx]], [[3czf]], [[3fqn]], [[3fqr]], [[3fqt]], [[3fqu]], [[3fqw]], [[3fqx]], [[3d25]], [[3bvn]], [[3dx6]], [[3dx7]], [[3dx8]], [[3dxa]], [[3bo8]], [[3bp4]], [[3bp7]], [[3bgm]], [[3bh8]], [[3bh9]], [[3bhb]], [[3b3i]], [[3b6s]], [[2rfx]], [[3bze]], [[3bzf]], [[3bw9]], [[3bwa]], [[3c9n]], [[2v2w]], [[2v2x]], [[2gt9]], [[2gtw]], [[2gtz]], [[2guo]], [[2nw3]], [[2fyy]], [[2fz3]], [[2hn7]], [[2cik]], [[2git]], [[2hjk]], [[2hjl]], [[2h6p]], [[2d31]], [[2c7u]], [[2bck]], [[2a83]], [[2axf]], [[2axg]], [[2bvo]], [[2bvp]], [[2bvq]], [[1s8d]], [[1t1w]], [[1t1x]], [[1t1y]], [[1t1z]], [[1t20]], [[1t21]], [[1t22]], [[1s7q]], [[1zsd]], [[2bsr]], [[2bss]], [[2bst]], [[1zhk]], [[1zhl]], [[1tvb]], [[1tvh]], [[1xr8]], [[1xr9]], [[1w0v]], [[1w0w]], [[1xh3]], [[1uxs]], [[1uxw]], [[1s9w]], [[1s9x]], [[1s9y]], [[1q94]], [[1qvo]], [[1n2r]], [[1ogt]], [[1qew]], [[1jge]], [[1k5n]], [[1i7r]], [[1i7t]], [[1i7u]], [[1jf1]], [[1jht]], [[1i4f]], [[1e27]], [[1e28]], [[1i1y]], [[1i1f]], [[1qqd]], [[1mhe]], [[1b0g]], [[1a9b]], [[1a9e]], [[1a1m]], [[1a1n]], [[1a1o]], [[1tmc]], [[2clr]], [[1hhg]], [[1hhh]], [[1hhi]], [[1hhj]], [[1hhk]], [[1hsb]], [[1hsa]], [[3kla]], [[3giv]], [[3d18]], [[3bxn]], [[1x7q]], [[1ydp]], [[1sys]], [[1of2]], [[1jgd]], [[1eey]], [[1eez]], [[1duy]], [[1duz]], [[1agb]], [[1agc]], [[1agd]], [[1age]], [[1agf]], [[3am8]], [[3qfd]], [[3rew]], [[3rl1]], [[3rl2]], [[3skm]], [[3sko]], [[3utq]], [[3uts]], [[3utt]], [[3vfm]], [[3vfn]], [[3vfo]], [[3vfp]], [[3vfr]], [[3vfs]], [[3vft]], [[3vfu]], [[3vfv]], [[3vfw]], [[3vh8]], [[2ypk]], [[3spv]], [[3tid]], [[3tie]], [[3to2]], [[3upr]], [[3v5d]], [[3v5h]], [[3v5k]], [[3vcl]], [[3vri]], [[3vrj]], [[4f7m]], [[4f7p]], [[4f7t]], [[4gks]], [[4i4w]], [[3w39]], [[4g8i]], [[4g9d]], [[4jqv]], [[4jqx]], [[4k7f]], [[1b0r]], [[3vxm]], [[3vxn]], [[3vxo]], [[3vxp]], [[3vxr]], [[3vxs]], [[3vxu]], [[3w0w]], [[4hwz]], [[4hx1]], [[4i48]], [[4nqv]], [[4nqx]], [[3wl9]], [[3wlb]], [[3ws3]], [[3ws6]], [[3x11]], [[3x12]], [[3x13]], [[3x14]], [[4hs3]], [[4lcy]], [[4lnr]], [[4mj5]], [[4mj6]], [[4nnx]], [[4nny]], [[4no2]], [[4no3]], [[4no5]], [[4nt6]], [[4o2c]], [[4o2e]], [[4o2f]], [[4pr5]], [[4pra]], [[4prb]], [[4prd]], [[4pre]], [[4prn]], [[4qrq]], [[4qrs]], [[4qrt]], [[4qru]], [[4u6x]], [[4u6y]], [[4uq2]], [[4uq3]], [[4wj5]], [[6ei2]], [[6bxp]], [[6at9]], [[6at5]], [[5xos]], [[5wxd]], [[5wxc]], [[5wwu]], [[5wwj]], [[5wwi]], [[5wsh]], [[5wjn]], [[5wjl]], [[5w6a]], [[5w69]], [[5w67]], [[5vz5]], [[5vge]], [[5vgd]], [[5v5m]], [[5v5l]], [[5u98]], [[5txs]], [[5opi]], [[5nmk]], [[5nmh]], [[5n6b]], [[5iue]], [[5gsx]], [[5gsv]], [[5gsr]], [[5gsd]], [[5gsb]], [[5grg]], [[5grd]], [[5gr7]], [[6mtl]], [[6mt6]], [[6mt5]], [[6mt4]], [[6mt3]], [[6gl1]], [[6ghn]], [[6gh4]], [[6gh1]], [[6ggm]], [[6gb7]], [[6g3j]], [[6d2t]], [[6d2r]], [[6d2b]], [[6d29]], [[6amt]], [[5wmr]], [[5wmq]], [[5wmp]], [[5wmo]], [[5wmn]], [[5vwj]], [[5vwh]], [[5vwf]], [[5vwd]], [[5vvp]], [[5vuf]], [[5vue]], [[5vud]], [[5ts1]], [[5trz]] - hβ-2-microglobulin + hMHC I α + peptide<br /> |
| + | **[[5nq3]], [[5nq2]], [[5nq1]], [[5nq0]], [[5npz]] - hβ-2-microglobulin + pMHC I + peptide<br /> | ||
**[[4l29]], [[4l3c]], [[5n1y]], [[5mer]], [[5meq]], [[5mep]], [[5meo]], [[5men]], [[5ind]], [[5inc]], [[5im7]], [[5iek]], [[5ieh]], [[5ib5]], [[5ib4]], [[5ib3]], [[5ib2]], [[5ib1]], [[5hhq]], [[5hhp]], [[5hho]], [[5hhn]], [[5hhm]], [[5hgh]], [[5hgd]], [[5hgb]], [[5hga]], [[5fdw]], [[5fa4]], [[5fa3]], [[5f9j]], [[5f7d]], [[5eu5]], [[5eu4]], [[5eu3]], [[5eot]], [[5eo1]], [[5eo0]], [[5enw]], [[5e00]], [[5deg]], [[5def]], [[5ddh]], [[5d9s]], [[5c0j]], [[5c0i]], [[5c0g]], [[5c0f]], [[5c0e]], [[5c0d]], [[4xxc]], [[4wu7]], [[4wu5]]. [[4wdi]], [[4u1s]], [[4u1n]], [[4u1m]], [[4u1l]], [[4u1k]], [[4u1j]], [[4u1i]], [[4u1h]] - hβ-2-microglobulin + hMHC I α + NY-ES01<br /> | **[[4l29]], [[4l3c]], [[5n1y]], [[5mer]], [[5meq]], [[5mep]], [[5meo]], [[5men]], [[5ind]], [[5inc]], [[5im7]], [[5iek]], [[5ieh]], [[5ib5]], [[5ib4]], [[5ib3]], [[5ib2]], [[5ib1]], [[5hhq]], [[5hhp]], [[5hho]], [[5hhn]], [[5hhm]], [[5hgh]], [[5hgd]], [[5hgb]], [[5hga]], [[5fdw]], [[5fa4]], [[5fa3]], [[5f9j]], [[5f7d]], [[5eu5]], [[5eu4]], [[5eu3]], [[5eot]], [[5eo1]], [[5eo0]], [[5enw]], [[5e00]], [[5deg]], [[5def]], [[5ddh]], [[5d9s]], [[5c0j]], [[5c0i]], [[5c0g]], [[5c0f]], [[5c0e]], [[5c0d]], [[4xxc]], [[4wu7]], [[4wu5]]. [[4wdi]], [[4u1s]], [[4u1n]], [[4u1m]], [[4u1l]], [[4u1k]], [[4u1j]], [[4u1i]], [[4u1h]] - hβ-2-microglobulin + hMHC I α + NY-ES01<br /> | ||
**[[1ktl]], [[3kww]], [[3h9h]], [[3ixa]], [[3gso]], [[3gsq]], [[3gsr]], [[3gsu]], [[3gsv]], [[3gsw]], [[3gsx]], [[3ft2]], [[3ft3]], [[3ft4]], [[2av1]], [[2av7]], [[1cg9]], [[1m05]], [[1m6o]], [[1kpr]], [[1ktl]], [[3kyn]], [[3kyo]], [[1qr1]] - β-2-microglobulin + hMHC I α (mutant) + peptide<br /> | **[[1ktl]], [[3kww]], [[3h9h]], [[3ixa]], [[3gso]], [[3gsq]], [[3gsr]], [[3gsu]], [[3gsv]], [[3gsw]], [[3gsx]], [[3ft2]], [[3ft3]], [[3ft4]], [[2av1]], [[2av7]], [[1cg9]], [[1m05]], [[1m6o]], [[1kpr]], [[1ktl]], [[3kyn]], [[3kyo]], [[1qr1]] - β-2-microglobulin + hMHC I α (mutant) + peptide<br /> | ||
**[[1syv]], [[1n2r]] - β-2-microglobulin + hMHC I + hMHC II peptide<br /> | **[[1syv]], [[1n2r]] - β-2-microglobulin + hMHC I + hMHC II peptide<br /> | ||
**[[1kjv]], [[1kjm]], [[1ed3]] – rβ-2-microglobulin + MHC I α + peptide<br /> | **[[1kjv]], [[1kjm]], [[1ed3]] – rβ-2-microglobulin + MHC I α + peptide<br /> | ||
| - | **[[3bev]], [[3bew]], [[4d0b]], [[5ad0]], [[2yez]], [[4d0c]], [[5acz]] - cβ-2-microglobulin + cMHC I α + peptide<br /> | + | **[[3bev]], [[3bew]], [[4d0b]], [[5ad0]], [[2yez]], [[4d0c]], [[5acz]], [[4d0d]], [[4cw1]], [[4cvz]], [[4cvx]] - cβ-2-microglobulin + cMHC I α + peptide<br /> |
| - | **[[1kbg]], [[3l3h]], [[3ftg]], [[3e6f]], [[3ecb]], [[3ch1]], [[3cch]], [[3cc5]], [[3cpl]], [[2zsv]], [[2zsw]], [[2zok]], [[2zol]], [[3buy]], [[2ve6]], [[2e7l]], [[2fo4]], [[2cii]], [[2fwo]], [[2f74]], [[1zt1]], [[1zt7]], [[1vgk]], [[1yn6]], [[1yn7]], [[1zhb]], [[1wbx]], [[1wby]], [[1wbz]], [[1rjy]], [[1rjz]], [[1rk0]], [[1rk1]], [[1t0m]], [[1t0n]], [[1s7q]], [[1s7r]], [[1s7s]], [[1s7t]], [[1s7u]], [[1s7v]], [[1s7w]], [[1s7x]], [[1lk2]], [[1kpu]], [[1kpv]], [[1n3n]], [[1nan]], [[1n59]], [[1n5a]], [[1ffn]], [[1ffo]], [[1ffp]], [[1g7p]], [[1g7q]], [[1lek]], [[1leg]], [[1inq]], [[1juf]], [[1k8d]], [[1jpf]], [[1jpg]], [[1fg2]], [[1qlf]], [[1bz9]], [[1kbg]], [[1hoc]], [[2mha]], [[1vad]], [[1vac]], [[3fol]], [[3fom]], [[3fon]], [[1ce6]], [[1osz]], [[1bii]], [[1ld9]], [[2vaa]], [[2vab]], [[3p4m]], [[3p4n]], [[3p4o]], [[3p9l]], [[3p9m]], [[3pab]], [[3pwu]], [[3pwv]], [[3quk]], [[3qul]], [[3rol]], [[3roo]], [[3vj6]], [[1ldp]], [[3tbs]], [[3tbt]], [[3tbv]], [[3tbw]], [[4nsk]], [[3tby]], [[4huu]], [[4huv]], [[4huw]], [[4hux]], [[4hv8]], [[4pg2]], [[4pg9]], [[4pgb]], [[4pgc]], [[4pgd]], [[4pge]], [[4pv8]], [[4pv9]], [[5swq]], [[5j6h]], [[5e8p]], [[5e8o]], [[5e8n]], [[4z78]], [[4z77]], [[4z76]], [[5wli]], [[5weu]], [[5wet]], [[5wes]], [[5wer]], [[4l8c]], [[4l8d]], [[5t7g]], [[5mzm]], [[5kd7]], [[5kd4]], [[5jwe]], [[5jwd]] - mβ-2-microglobulin + mMHC I + peptide<br /> | + | **[[1kbg]], [[3l3h]], [[3ftg]], [[3e6f]], [[3ecb]], [[3ch1]], [[3cch]], [[3cc5]], [[3cpl]], [[2zsv]], [[2zsw]], [[2zok]], [[2zol]], [[3buy]], [[2ve6]], [[2e7l]], [[2fo4]], [[2cii]], [[2fwo]], [[2f74]], [[1zt1]], [[1zt7]], [[1vgk]], [[1yn6]], [[1yn7]], [[1zhb]], [[1wbx]], [[1wby]], [[1wbz]], [[1rjy]], [[1rjz]], [[1rk0]], [[1rk1]], [[1t0m]], [[1t0n]], [[1s7q]], [[1s7r]], [[1s7s]], [[1s7t]], [[1s7u]], [[1s7v]], [[1s7w]], [[1s7x]], [[1lk2]], [[1kpu]], [[1kpv]], [[1n3n]], [[1nan]], [[1n59]], [[1n5a]], [[1ffn]], [[1ffo]], [[1ffp]], [[1g7p]], [[1g7q]], [[1lek]], [[1leg]], [[1inq]], [[1juf]], [[1k8d]], [[1jpf]], [[1jpg]], [[1fg2]], [[1qlf]], [[1bz9]], [[1kbg]], [[1hoc]], [[2mha]], [[1vad]], [[1vac]], [[3fol]], [[3fom]], [[3fon]], [[1ce6]], [[1osz]], [[1bii]], [[1ld9]], [[2vaa]], [[2vab]], [[3p4m]], [[3p4n]], [[3p4o]], [[3p9l]], [[3p9m]], [[3pab]], [[3pwu]], [[3pwv]], [[3quk]], [[3qul]], [[3rol]], [[3roo]], [[3vj6]], [[1ldp]], [[3tbs]], [[3tbt]], [[3tbv]], [[3tbw]], [[4nsk]], [[3tby]], [[4huu]], [[4huv]], [[4huw]], [[4hux]], [[4hv8]], [[4pg2]], [[4pg9]], [[4pgb]], [[4pgc]], [[4pgd]], [[4pge]], [[4pv8]], [[4pv9]], [[5swq]], [[5j6h]], [[5e8p]], [[5e8o]], [[5e8n]], [[4z78]], [[4z77]], [[4z76]], [[5wli]], [[5weu]], [[5wet]], [[5wes]], [[5wer]], [[4l8c]], [[4l8d]], [[5t7g]], [[5mzm]], [[5kd7]], [[5kd4]], [[5jwe]], [[5jwd]], [[6gb6]], [[6gb5]] - mβ-2-microglobulin + mMHC I + peptide<br /> |
| - | **[[5vcl]] - | + | **[[5vcl]] - mβ-2-microglobulin + H2-T23 + peptide<br /> |
**[[2qri]], [[3nwm]] - mβ-2-microglobulin/mMHC I/peptide<br /> | **[[2qri]], [[3nwm]] - mβ-2-microglobulin/mMHC I/peptide<br /> | ||
**[[2qrs]], [[2qrt]] - mβ-2-microglobulin/mMHC I (mutant)/peptide<br /> | **[[2qrs]], [[2qrt]] - mβ-2-microglobulin/mMHC I (mutant)/peptide<br /> | ||
**[[1ypz]], [[1mhc]], [[2clv]], [[2clz]], [[1fzj]], [[1fzk]], [[1fzm]], [[1fzo]], [[1ddh]], [[4iho]], [[4l8b]], - mβ-2-microglobulin + mMHC II + TCR<br /> | **[[1ypz]], [[1mhc]], [[2clv]], [[2clz]], [[1fzj]], [[1fzk]], [[1fzm]], [[1fzo]], [[1ddh]], [[4iho]], [[4l8b]], - mβ-2-microglobulin + mMHC II + TCR<br /> | ||
**[[4l4t]], [[4l4v]], [[4nqc]], [[4nqd]], [[4nqe]], [[5pj5]], [[4pj7]], [[5pj8]], [[4pj9]], [[5pja]], [[4pjb]], [[5pjc]], [[4pjd]], [[5pje]], [[4pjf]], [[5pjg]], [[4pjh]], [[5pji]], [[4pjx]], [[4prh]], [[4pri]], [[4wo4]], [[5u72]], [[5u6q]], [[5u2v]], [[5u17]], [[5u16]], [[5d7l]], [[5d7j]], [[5d7i]], [[5d5m]], [[4pji]], [[4pjg]], [[4pje]], [[4pjc]], [[4pja]], [[4pj8]], [[4pj5]], [[5nmg]] - hβ-2-microglobulin + hMHC I + TCR<br /> | **[[4l4t]], [[4l4v]], [[4nqc]], [[4nqd]], [[4nqe]], [[5pj5]], [[4pj7]], [[5pj8]], [[4pj9]], [[5pja]], [[4pjb]], [[5pjc]], [[4pjd]], [[5pje]], [[4pjf]], [[5pjg]], [[4pjh]], [[5pji]], [[4pjx]], [[4prh]], [[4pri]], [[4wo4]], [[5u72]], [[5u6q]], [[5u2v]], [[5u17]], [[5u16]], [[5d7l]], [[5d7j]], [[5d7i]], [[5d5m]], [[4pji]], [[4pjg]], [[4pje]], [[4pjc]], [[4pja]], [[4pj8]], [[4pj5]], [[5nmg]] - hβ-2-microglobulin + hMHC I + TCR<br /> | ||
| - | **[[3qq3]], [[3qq4]], [[5h94]] - β-2-microglobulin + MHC I + peptide - pig<br /> | + | **[[3qq3]], [[3qq4]], [[5h94]], [[5ylx]] - β-2-microglobulin + MHC I + peptide - pig<br /> |
**[[4gkn]], [[6bxq]] - β-2-microglobulin + MHC I + peptide – gorilla<br /> | **[[4gkn]], [[6bxq]] - β-2-microglobulin + MHC I + peptide – gorilla<br /> | ||
| - | **[[5f1n]] - β-2-microglobulin + MHC I + peptide – dog<br /> | + | **[[5f1n]], [[5f1i]] - β-2-microglobulin + MHC I + peptide – dog<br /> |
**[[4zuw]], [[4zuv]], [[4zuu]], [[4zut]], [[4zus]] - β-2-microglobulin + MHC I + peptide – horse<br /> | **[[4zuw]], [[4zuv]], [[4zuu]], [[4zut]], [[4zus]] - β-2-microglobulin + MHC I + peptide – horse<br /> | ||
**[[4zfz]] - β-2-microglobulin + MHC I + peptide – rhesus macaque<br /> | **[[4zfz]] - β-2-microglobulin + MHC I + peptide – rhesus macaque<br /> | ||
| - | **[[5gjy]], [[5gjx]] - -2-microglobulin + MHC I + peptide – rhesus mallard<br /> | + | **[[5gjy]], [[5gjx]] - β-2-microglobulin + MHC I + peptide – rhesus mallard<br /> |
| - | **[[5h5z]], [[5y91]] - | + | **[[5h5z]], [[5y91]] - gcβ-2-microglobulin + MHC I + peptide <br /> |
**[[1nez]] - mβ-2-microglobulin + mMHC I + CD8 α chain<br /> | **[[1nez]] - mβ-2-microglobulin + mMHC I + CD8 α chain<br /> | ||
| - | **[[5xmm]] - | + | **[[5xmm]] - cβ-2-microglobulin + MHC I + gag polyprotein - cat <br /> |
| - | **[[5xmf]] - | + | **[[5xmf]] - cβ-2-microglobulin + MHC I + peptide <br /> |
*B2M in ternary complex with CD1 | *B2M in ternary complex with CD1 | ||
| - | **[[3qux]], [[3quy]], [[3quz]], [[3o8x]], [[3o9w]], [[4mng]], [[3qi9]], [[3scm]], [[3sda]], [[3sdc]], [[3ta3]], [[3tn0]], [[3to4]], [[3tvm]], [[3sdd]], [[4elm]], [[3rtq]], [[3rzc]], [[4ei5]], [[4apq]], [[4zak]], [[4y4k]], [[4y4h]], [[4y4f]], [[4y2d]], [[4y16]] - mβ-2-microglobulin + T cell receptor + CD1D1<BR /> | + | **[[3qux]], [[3quy]], [[3quz]], [[3o8x]], [[3o9w]], [[4mng]], [[3qi9]], [[3scm]], [[3sda]], [[3sdc]], [[3ta3]], [[3tn0]], [[3to4]], [[3tvm]], [[3sdd]], [[4elm]], [[3rtq]], [[3rzc]], [[4ei5]], [[4apq]], [[4zak]], [[4y4k]], [[4y4h]], [[4y4f]], [[4y2d]], [[4y16]], [[5vcj]] - mβ-2-microglobulin + T cell receptor + CD1D1<BR /> |
| - | **[[2po6]], [[3vwj]], [[3vwk]], [[4en3]], [[3sdx]], [[3tzv]], [[4lhu]], [[4ww2]] - hβ-2-microglobulin + TCR + CD1D1<BR /> | + | **[[2po6]], [[3vwj]], [[3vwk]], [[4en3]], [[3sdx]], [[3tzv]], [[4lhu]], [[4ww2]], [[4wwk]] - hβ-2-microglobulin + TCR + CD1D1<BR /> |
**[[4x6c]], [[4x6d]] - hβ-2-microglobulin + TCR + CD1A<br /> | **[[4x6c]], [[4x6d]] - hβ-2-microglobulin + TCR + CD1A<br /> | ||
| - | **[[5l2k]] - hβ-2-microglobulin + TCR + CD1B<br /> | + | **[[5l2k]], [[6cug]] - hβ-2-microglobulin + TCR + CD1B<br /> |
**[[3dbx]] - cβ-2-microglobulin + CD1-2 + fatty acid<BR /> | **[[3dbx]] - cβ-2-microglobulin + CD1-2 + fatty acid<BR /> | ||
**[[1zhn]] - mβ-2-microglobulin + CD1D1 + phosphatidylcholine<BR /> | **[[1zhn]] - mβ-2-microglobulin + CD1D1 + phosphatidylcholine<BR /> | ||
| - | **[[5tw5]], [[5tw2]] - | + | **[[5tw5]], [[5tw2]] - mβ-2-microglobulin + CD1D1 + glycosphinglipid<br /> |
**[[1zt4]] - mβ-2-microglobulin + CD1D1 + ceramide derivative<br /> | **[[1zt4]] - mβ-2-microglobulin + CD1D1 + ceramide derivative<br /> | ||
**[[3ubx]], [[4irj]], [[4irs]] - mβ-2-microglobulin + FAB + CD1D1<br /> | **[[3ubx]], [[4irj]], [[4irs]] - mβ-2-microglobulin + FAB + CD1D1<br /> | ||
| Line 131: | Line 140: | ||
**[[3m17]], [[3m1b]] - hβ-2-microglobulin + FcRn+ peptide<br /> | **[[3m17]], [[3m1b]] - hβ-2-microglobulin + FcRn+ peptide<br /> | ||
**[[4k71]], [[4n0f]], [[4n0u]] - hβ-2-microglobulin + serum albumin + Igg receptor P51<br /> | **[[4k71]], [[4n0f]], [[4n0u]] - hβ-2-microglobulin + serum albumin + Igg receptor P51<br /> | ||
| - | **[[5whk]] - | + | **[[5whk]], [[66fgb]] - hβ-2-microglobulin + antibody + Igg receptor P51<br /> |
| - | **[[5bjt]] - | + | **[[5bjt]] - hβ-2-microglobulin + peptide + Igg receptor P51<br /> |
*B2M in quaternary complex with MHC | *B2M in quaternary complex with MHC | ||
**[[5d2n]], [[5knm]], [[2dyp]] - hβ-2-microglobulin + hMHC I α + C25 + peptide<br /> | **[[5d2n]], [[5knm]], [[2dyp]] - hβ-2-microglobulin + hMHC I α + C25 + peptide<br /> | ||
| + | **[[6ewo]], [[6ewc]], [[6ewa]] - hβ-2-microglobulin + hMHC I + LIR-1 + peptide<br /> | ||
**[[1p7q]], [[1im9]] - hβ-2-microglobulin + hMHC I α + leukocyte immunoglobulin-like receptor + peptide<br /> | **[[1p7q]], [[1im9]] - hβ-2-microglobulin + hMHC I α + leukocyte immunoglobulin-like receptor + peptide<br /> | ||
**[[2dyp]] - hβ-2-microglobulin + hMHC I α (mutant) + leukocyte immunoglobulin-like receptor + peptide<br /> | **[[2dyp]] - hβ-2-microglobulin + hMHC I α (mutant) + leukocyte immunoglobulin-like receptor + peptide<br /> | ||
| Line 142: | Line 152: | ||
**[[1im3]] - hβ-2-microglobulin + hMHC I α + cytomegalovirus protein US2 + peptide<br /> | **[[1im3]] - hβ-2-microglobulin + hMHC I α + cytomegalovirus protein US2 + peptide<br /> | ||
**[[3cii]], [[3cdg]] - hβ-2-microglobulin + hMHC I α + CD94 ectodomain + NKG2A/NKG2B integral membrane protein + peptide<br /> | **[[3cii]], [[3cdg]] - hβ-2-microglobulin + hMHC I α + CD94 ectodomain + NKG2A/NKG2B integral membrane protein + peptide<br /> | ||
| - | **[[3hae]], [[3gjf]], [[3cvh]], [[1w72]] - hβ-2-microglobulin + hMHC I α + antibody + peptide<br /> | + | **[[3hae]], [[3gjf]], [[3cvh]], [[1w72]], [[6id4]] - hβ-2-microglobulin + hMHC I α + antibody + peptide<br /> |
**[[4eup]], [[4jfd]], [[4jfe]], [[4jff]], [[4jfo]], [[4jfp]], [[4jfq]] - hβ-2-microglobulin +MHC I + JKF6 + melanoma peptide<br /> | **[[4eup]], [[4jfd]], [[4jfe]], [[4jff]], [[4jfo]], [[4jfp]], [[4jfq]] - hβ-2-microglobulin +MHC I + JKF6 + melanoma peptide<br /> | ||
**[[4ftv]] - hβ-2-microglobulin +MHC I + A6 + protein TAX-1 peptide<br /> | **[[4ftv]] - hβ-2-microglobulin +MHC I + A6 + protein TAX-1 peptide<br /> | ||
| Line 156: | Line 166: | ||
*B2M in quaternary complex with MHC and T cell receptor | *B2M in quaternary complex with MHC and T cell receptor | ||
| - | **[[3qdg]], [[3qdj]], [[3qdm]], [[3qeq]], [[3mv7]], [[3mv8]], [[3mv9]], [[3h9s]], [[3gsn]], [[3d39]], [[3d3v]], [[3ffc]], [[2vlj]], [[2vlk]], [[2vll]], [[2vlr]], [[2j8u]], [[2p5e]], [[2p5w]], [[2pye]], [[2gj6]], [[2f54]], [[2esv]], [[2bnq]], [[2bnr]], [[1lp9]], [[1oga]], [[1mi5]], [[1qrn]], [[2nx5]], [[2ak4]], [[1qse]], [[1qsf]], [[1bd2]], [[1ao7]], [[2ypl]], [[4g8g]], [[4g9f]], [[4jrx]], [[4jry]], [[5jhd]], [[5swz]], [[5sws]], [[5isz]], [[5hyj]], [[5euo]], [[5eu6]], [[5e9d]], [[5e6i]], [[3sjv]], [[5d2l]], [[5c0c]], [[5c0b]], [[5c0a]], [[5c09]], [[5c08]], [[5c07]], [[5bs0]], [[5brz]], [[4g8g]], [[4g9f]], [[4jrx]], [[4jry]], [[5jhd]], [[5swz]], [[5sws]], [[5isz]], [[5hyj]], [[5euo]], [[5eu6]], [[5e9d]], [[5e6i]], [[3sjv]], [[5d2l]], [[5c0c]], [[5c0b]], [[5c0a]], [[5c09]], [[5c08]], [[5c07]], [[5bs0]], [[5brz]], [[5jzi]], [[3kxf]], [[3mv8]], [[2jcc]], [[2uwe]], [[6avg]], [[6avf]], [[5xov]], [[5xot]], [[5wkh]], [[5wkf]], [[5w1w]], [[5w1v]], [[4mji]], [[4prp]], [[4qok]], [[4qrp]], [[4qrr]], [[5tez]], [[5nmf]], [[5nme]] - hβ-2-microglobulin + hMHC I + TCR + peptide<br /> | + | **[[3qdg]], [[3qdj]], [[3qdm]], [[3qeq]], [[3mv7]], [[3mv8]], [[3mv9]], [[3h9s]], [[3gsn]], [[3d39]], [[3d3v]], [[3ffc]], [[2vlj]], [[2vlk]], [[2vll]], [[2vlr]], [[2j8u]], [[2p5e]], [[2p5w]], [[2pye]], [[2gj6]], [[2f54]], [[2esv]], [[2bnq]], [[2bnr]], [[1lp9]], [[1oga]], [[1mi5]], [[1qrn]], [[2nx5]], [[2ak4]], [[1qse]], [[1qsf]], [[1bd2]], [[1ao7]], [[2ypl]], [[4g8g]], [[4g9f]], [[4jrx]], [[4jry]], [[5jhd]], [[5swz]], [[5sws]], [[5isz]], [[5hyj]], [[5euo]], [[5eu6]], [[5e9d]], [[5e6i]], [[3sjv]], [[5d2l]], [[5c0c]], [[5c0b]], [[5c0a]], [[5c09]], [[5c08]], [[5c07]], [[5bs0]], [[5brz]], [[4g8g]], [[4g9f]], [[4jrx]], [[4jry]], [[5jhd]], [[5swz]], [[5sws]], [[5isz]], [[5hyj]], [[5euo]], [[5eu6]], [[5e9d]], [[5e6i]], [[3sjv]], [[5d2l]], [[5c0c]], [[5c0b]], [[5c0a]], [[5c09]], [[5c08]], [[5c07]], [[5bs0]], [[5brz]], [[5jzi]], [[3kxf]], [[3mv8]], [[2jcc]], [[2uwe]], [[6avg]], [[6avf]], [[5xov]], [[5xot]], [[5wkh]], [[5wkf]], [[5w1w]], [[5w1v]], [[4mji]], [[4prp]], [[4qok]], [[4qrp]], [[4qrr]], [[5tez]], [[5nmf]], [[5nme]], [[6mtm]], [[6eqb]], [[6eqa]], [[6bj8]], [[6bj3]], [[6bj2]], [[6amu]], [[6am5]], [[5yxu]], [[5yxn]], [[5nqk]], [[5nht]] - hβ-2-microglobulin + hMHC I + TCR + peptide<br /> |
**[[2f53]] - hβ-2-microglobulin (mutant) + hMHC I α + TCR + peptide<br /> | **[[2f53]] - hβ-2-microglobulin (mutant) + hMHC I α + TCR + peptide<br /> | ||
**[[5u1r]] - hβ-2-microglobulin + hMHC I + TCR + diclofenac<br /> | **[[5u1r]] - hβ-2-microglobulin + hMHC I + TCR + diclofenac<br /> | ||
| Line 174: | Line 184: | ||
**[[3d2u]] - hβ-2-microglobulin + UL18 + leukocyte immunoglobulin-like receptor + peptide<br /> | **[[3d2u]] - hβ-2-microglobulin + UL18 + leukocyte immunoglobulin-like receptor + peptide<br /> | ||
| - | **[[6eny]] - | + | **[[6eny]] - hβ-2-microglobulin + MHC I + tapasin + protein disulfide isomerase – Cryo EM<br /> |
}} | }} | ||
Revision as of 08:32, 3 April 2019
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3D Structures of β-2 microglobulin
Updated on 03-April-2019
References
- ↑ Liu C, Sawaya MR, Eisenberg D. beta-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages. Nat Struct Mol Biol. 2011 Jan;18(1):49-55. Epub 2010 Dec 5. PMID:21131979 doi:10.1038/nsmb.1948
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Joel L. Sussman, Alexander Berchansky, David Canner
