Beta-adrenergic receptor kinase
From Proteopedia
| Line 5: | Line 5: | ||
<scene name='70/705677/Cv/5'>Mg+2 ion coordination site</scene> (PDB code [[3uzt]]).<ref>PMID:22727813</ref> | <scene name='70/705677/Cv/5'>Mg+2 ion coordination site</scene> (PDB code [[3uzt]]).<ref>PMID:22727813</ref> | ||
| + | |||
| + | == 3D Structures of β adrenergic receptor kinase == | ||
| + | [[Beta adrenergic receptor kinase 3D structures]] | ||
| + | |||
</StructureSection> | </StructureSection> | ||
== 3D Structures of β adrenergic receptor kinase == | == 3D Structures of β adrenergic receptor kinase == | ||
| Line 13: | Line 17: | ||
[[5uvc]], [[5uuu]] – hBARK1 + inhibitor - human <BR /> | [[5uvc]], [[5uuu]] – hBARK1 + inhibitor - human <BR /> | ||
[[4pnk]], [[3cik]], [[5he3]] – hBARK1 + guanine-nucleotide binding protein G β,γ subunits <BR /> | [[4pnk]], [[3cik]], [[5he3]] – hBARK1 + guanine-nucleotide binding protein G β,γ subunits <BR /> | ||
| - | [[3psc]], [[5he0]], [[5he1]], [[5he2]] – hBARK1 (mutant) + guanine-nucleotide binding protein G β,γ subunits <BR /> | + | [[3psc]], [[5he0]], [[5he1]], [[5he2]], [[6c2y]] – hBARK1 (mutant) + guanine-nucleotide binding protein G β,γ subunits <BR /> |
[[4mk0]], [[3v5w]] – hBARK1 + guanine-nucleotide binding protein G β,γ subunits + paroxetine derivative<BR /> | [[4mk0]], [[3v5w]] – hBARK1 + guanine-nucleotide binding protein G β,γ subunits + paroxetine derivative<BR /> | ||
[[3uzs]] – hBARK1 (mutant) + guanine-nucleotide binding protein G β,γ subunits + RNA <BR /> | [[3uzs]] – hBARK1 (mutant) + guanine-nucleotide binding protein G β,γ subunits + RNA <BR /> | ||
Revision as of 08:50, 3 April 2019
| |||||||||||
3D Structures of β adrenergic receptor kinase
Updated on 03-April-2019
1ym7 – bBARK1 (mutant) - bovine
5uvc, 5uuu – hBARK1 + inhibitor - human
4pnk, 3cik, 5he3 – hBARK1 + guanine-nucleotide binding protein G β,γ subunits
3psc, 5he0, 5he1, 5he2, 6c2y – hBARK1 (mutant) + guanine-nucleotide binding protein G β,γ subunits
4mk0, 3v5w – hBARK1 + guanine-nucleotide binding protein G β,γ subunits + paroxetine derivative
3uzs – hBARK1 (mutant) + guanine-nucleotide binding protein G β,γ subunits + RNA
3uzt – hBARK1 (mutant) + RNA
3krw, 3krx, 5wg3, 5wg4, 5wg5, 5ukk, 5ukl, 5he3 – hBARK1 + guanine-nucleotide binding protein G β,γ subunits + inhibitor
3pvu, 3pvw, 5ukm, 5he0, 5he1, 5he2 – bBARK1 (mutant) + guanine-nucleotide binding protein G β,γ subunits + inhibitor
2bcj – bBARK1 (mutant) + guanine-nucleotide binding protein G α,β,γ subunits
1omw – bBARK1 (mutant) + guanine-nucleotide binding protein G β,γ subunits
References
- ↑ Benovic JL, Strasser RH, Caron MG, Lefkowitz RJ. Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor. Proc Natl Acad Sci U S A. 1986 May;83(9):2797-801. PMID:2871555
- ↑ Tesmer VM, Lennarz S, Mayer G, Tesmer JJ. Molecular Mechanism for Inhibition of G Protein-Coupled Receptor Kinase 2 by a Selective RNA Aptamer. Structure. 2012 Jun 21. PMID:22727813 doi:10.1016/j.str.2012.05.002
Proteopedia Page Contributors and Editors (what is this?)
Michal Harel, Alexander Berchansky, Cristina Murga, Joel L. Sussman
