This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6fz6
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6fz6 is ON HOLD Authors: Description: Category: Unreleased Structures) |
|||
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of a radical SAM methyltransferase from Sphaerobacter thermophilus== | |
| - | + | <StructureSection load='6fz6' size='340' side='right'caption='[[6fz6]], [[Resolution|resolution]] 1.42Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6fz6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FZ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FZ6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SMC:S-METHYLCYSTEINE'>SMC</scene></td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/23S_rRNA_(adenine(2503)-C(2))-methyltransferase 23S rRNA (adenine(2503)-C(2))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.192 2.1.1.192] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fz6 OCA], [http://pdbe.org/6fz6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fz6 RCSB], [http://www.ebi.ac.uk/pdbsum/6fz6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fz6 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/D1C4T7_SPHTD D1C4T7_SPHTD]] Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.[HAMAP-Rule:MF_01849][SAAS:SAAS00721833] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Hinchliffe, P]] | ||
| + | [[Category: Shaw, J M]] | ||
| + | [[Category: Spencer, J]] | ||
| + | [[Category: Antibiotic resistance]] | ||
| + | [[Category: Methyltransferase]] | ||
| + | [[Category: Radical sam]] | ||
| + | [[Category: Rrna]] | ||
| + | [[Category: Transferase]] | ||
Current revision
Crystal Structure of a radical SAM methyltransferase from Sphaerobacter thermophilus
| |||||||||||
