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6fz6
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of a radical SAM methyltransferase from Sphaerobacter thermophilus== | |
| - | + | <StructureSection load='6fz6' size='340' side='right'caption='[[6fz6]], [[Resolution|resolution]] 1.42Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6fz6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FZ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FZ6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SMC:S-METHYLCYSTEINE'>SMC</scene></td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/23S_rRNA_(adenine(2503)-C(2))-methyltransferase 23S rRNA (adenine(2503)-C(2))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.192 2.1.1.192] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fz6 OCA], [http://pdbe.org/6fz6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fz6 RCSB], [http://www.ebi.ac.uk/pdbsum/6fz6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fz6 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/D1C4T7_SPHTD D1C4T7_SPHTD]] Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.[HAMAP-Rule:MF_01849][SAAS:SAAS00721833] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Hinchliffe, P]] | ||
| + | [[Category: Shaw, J M]] | ||
| + | [[Category: Spencer, J]] | ||
| + | [[Category: Antibiotic resistance]] | ||
| + | [[Category: Methyltransferase]] | ||
| + | [[Category: Radical sam]] | ||
| + | [[Category: Rrna]] | ||
| + | [[Category: Transferase]] | ||
Current revision
Crystal Structure of a radical SAM methyltransferase from Sphaerobacter thermophilus
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